A 93-year-old Caucasian female presented with a hemorrhagic nodule in the right nasolabial sulcus. The patient stated that the lesion had been present for a year and it had increased in size gradually. The hemorrhagic nodule was asymptomatic except for occasional bleeding. Physical examination of the patient revealed an ulcerated and hyperpigmented nodule with a size of 2x1x1 cm in the right na...

Brown and black spots are present on the skin of all people. Melanomas compromise only a very small percentage of all such pigmented lesions but are responsible for most of the deaths and illness caused by pigment cells. Three types of melanomas can be distinguished from their clinical, histologic, and biologic characteristics: lentigo maligna, superficial spreading melanoma, and nodular melano...

Introduction. Melanoma is the most dangerous form of skin cancer. Morbidity from melanoma is increasing every year. Previous studies have revealed that there are some demographic and clinical factors having effect on melanoma survival prognosis. Aim of the study. Purpose of our study was to assess melanoma survival depending on prognostic factors, such as age, sex, stage, depth, histology and a...

PURPOSE The present study determined the clinical characteristics and prognostic factors in patients with malignant melanoma based on a series of 82 cases from January 2009 to December 2014 in Southwest Hospital and a meta-analysis (including 12 articles) involving 958 patients in China. MATERIALS AND METHODS The database elements included basic demographic data and prognosticators which were...

Spitzoid melanoma is a subtype of melanoma that, clinically and histologically, resembles a Spitz nevus. Clinically, spitzoid melanomas usually evolve from amelanotic nodular lesions, growing to 1 cm or more in diameter. They often remain clinically undiagnosed because of their wide variety of clinical appearances and a lack of pigmentation. Distinguishing a Spitz nevus from a spitzoid melanoma...

TVEC: Talimogene laherparepvec INTRODUCTION Inflammatory melanoma was first described in 1984 in 2 patients presenting with nodular cutaneous melanomas resected from the back followed 4 to 12 months later by recurrence in the form of diffuse, indurated, erythematous skin 20-25 cm in diameter with scattered nodularity. Microscopic examination found melanoma cells in the dermis and dermal lymphat...

BACKGROUND Sclerosing angiomatoid nodular transformation is a benign disorder of splenic tissue and is often mistaken as a potentially malignant entity in the diagnostic process. To the best of our knowledge, this is the first report of sclerosing angiomatoid nodular transformation mimicking metastasis of melanoma in the literature. CASE PRESENTATION A 43-year-old white man presented with a n...

BACKGROUND Malignant melanoma is a very rare paediatric tumour. This study was performed in order to understand clinical features and prognosis of malignant melanoma in children and adolescents. METHODS 443 patients ⩽ 18 years of age with malignant melanoma were prospectively registered with the German Central Malignant Melanoma Registry between 1983 and 2011. Cases were collected from 58 par...

In the present investigation, a total number of 22 sheep and 29 goats were surveyed for abnormal masses showed frequently on the skin areas (ears, lips, trunk and perineal region) and eyes (either unilateral or bilateral) of both animals. A characteristic clinical signs represented as cachexia, emaciation, anemia and exophthalmic eye or both eyes. The excised masses appeared grossly as nodular ...