Prurigo nodularis (PN) is a benign neurodermatitis of unknown etiology characterized by firm, hyperkeratotic pruritic nodules most commonly localized symmetrically on the bilateral extensor lower extremities. PN represents a primary dermatological condition or a dermatological manifestation of repeated traumatic manipulation secondary to chronic pruritus. One must consider underlying causes of ...

Thalidomide, a hypnosedative drug introduced in the 1950, has been used in a variety of dermatologic conditions during the past few decades. Although originally withbrawn from world market on discovery of its teratogenic effect, it has since been selectively reintroduced for use in various disorders thought to have an autoimmune or inflammatory basis. A review of the literature focused on clini...

Accepted: October 1, 2017 ABSTRACT It has been emphasized that prurigo simplex subacuta may be associated with various disorders and may be clinically confused with dermatitis herpetiformis. Aim of the study was to evaluate the value of our set of tests for finding possible associations and for the aforementioned differential diagnosis. Rates of implementations and abnormal results in our set o...

Most patients with localized nodules should receive topical treatment first. But disappointing results or specific findings described here could necessitate additional or alternative options.