The cancer stem cell (CSC) model posits the presence of a small number of CSCs in the heterogeneous cancer cell population that are ultimately responsible for tumor initiation, as well as cancer recurrence and metastasis. CSCs have been isolated from a variety of human cancers and are able to generate a hierarchical and heterogeneous cancer cell population. CSCs are also resistant to convention...

The review provides up-to-date data on effects of non-modifiable (sex, age) and modifiable (smoking, alcohol consumption, obesity, vitamin D deficiency, marital status, physical activity, depression) non-radiation risk factors incidence risks arterial hypertension. also refers to scientific evidence the impact ionizing radiation

Radiation is the emission or transmission of energy as waves particles through space a material medium which able to penetrate various materials and often categorized either ionizing non-ionizing depending on radiated particles. processing can be defined exposure with high radiation change their physical, chemical, biological characteristics, increase usefulness, safety purpose, reduce harmful ...

Background and Objective: The cell division cycle 25 (CDC25)is a familyof highly conserved dual-specificity phosphatases that activate cyclin-dependent kinase complexes. These complexes are the main cell cycle regulators. Mammalian cells ,exposure to DNA damaging radiations such as ionizing radiation and ultraviolet light, prevent cell cycle progression by activation of checkpoint pathways an...

the purpose of the research was determine the effects of gamma ray on seed germination, seedling height and root length of rice (oryza sativa l. spp. indica cv. mr219) to identify the lethal dosage of the radiation. paddy seeds of mr219 were exposed to different doses of gamma radiations viz 50,100,150,200,250,300,350,400,450,500,600,700,800,900 and 1000 gy using 60co as the radiation source. t...

background: our purpose was to investigate propolis and its component caffeic acid phenethyl ester (cape) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation (ir). materials and methods: fifty-four male albino sprague-dawley rats, divided into six groups, were designed as normal control group, cranial irradiation of 5 gray alone, irradiation plus cape, irradi...

Ionizing radiation is useful for the conservation and disinfestation of fresh and dried fruits. The treatment of fruits with gamma-rays or beams of accelerated electrons has been carefully tested and was recommended by FAO/WHO Codex Alimentarius Commission for the common use as an effective and safe preservation method [1]. It was found earlier that the ionizing radiation produces stable EPR si...

Trypanosoma cruzi, the causative agent of Chagas disease, is extremely resistant to ionizing radiation, enduring up to 1.5 kGy of gamma rays. Ionizing radiation can damage the DNA molecule both directly, resulting in double-strand breaks, and indirectly, as a consequence of reactive oxygen species production. After a dose of 500 Gy of gamma rays, the parasite genome is fragmented, but the chrom...