Abstract Despite the important role of written language in everyday life, abnormalities functional communication have been sparsely investigated primary progressive aphasia. Prior studies analyzed separately each three variants aphasia – but rarely compared them to other or spoken language. Manual analysis can be a time-consuming process. We therefore developed program which quantifies content ...

The term frontotemporal dementia (FTD) encompasses a range of clinical syndromes that are believed not to map reliably onto the spectrum of recognized pathologies. This study reexamines the relationships between clinical and pathological subtypes of FTD in a large series from two centers (n = 61). Clinical subtypes defined were behavioral variant FTD (n = 26), language variants (semantic dement...

In the early stages of neurodegenerative disorders, individuals may exhibit a decline in language abilities that is difficult to quantify with standardized tests. Careful analysis of connected speech can provide valuable information about a patient's language capacities. To date, this type of analysis has been limited by its time-consuming nature. In this study, we present a method for evaluati...

BACKGROUND/AIMS Primary progressive aphasia (PPA) comprises 2 main variants: semantic dementia (SD) and progressive nonfluent aphasia (PNFA). Addenbrooke's Cognitive Examination (ACE) has become widely used for the diagnosis of dementias. Less information, however, is available about its ability to detect and monitor changes in cognition in PPA. We aimed to analyse the sensitivity and longitudi...

This paper presents experiments in automatically diagnosing primary progressive aphasia (PPA) and two of its subtypes, semantic dementia (SD) and progressive nonfluent aphasia (PNFA), from the acoustics of recorded narratives and textual analysis of the resultant transcripts. In order to train each of three types of classifier (naı̈ve Bayes, support vector machine, random forest), a large set of...