Primary rat hepatocyte culture cells were used to study the acute regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity in response to 25-hydroxycholesterol, 3 beta,5 alpha,6 beta-cholestantriol, and mevalonolactone. All three effectors caused a rapid suppression of HMG-CoA reductase activity. 25-Hydroxycholesterol also caused an increase in the ratio of newly synthes...

white matter lesions (wmls) are commonly observed in strokepatients with small vessel disease (svd) and are thought toresult from a progressive, irreversible disease process followingarteriolosclerosis. in this study, we report a case of partialdisappearance of wmls 1 year after a lacunar stroke in a69-year-old man with evidence of svd. we also discuss possiblemechanisms associated with this ob...

background & aims of the study: recent studies indicated that particulate matter can have the lung irritation, chronic lung diseases, lung tissue, etc. the aim objective of this study was to assess the mortality associated with exposure to pm10 concentrations in ilam, iran, during 2013. materials & methods: pm10 data were taken from ilam's local agency of environment (i-lae). the annual mo...

abstract introduction: due to environmental and human health concerns related to humic acid (ha), mainly leading to disinfection by-products creation, removal or reduction of this matters is a necessary for drinking water suppliers. based on resistive economy map road and move to self-sufficiency, it is necessary to produce our need in water treatment industry. one of the main consumed material...

in a semiarid region of central iran, effects of parent materials, physiography and landscape position, land use, andmanagement practices on association of organic carbon with secondary (aggregates) particles and aggregate stability canhave important consequences in terms of carbon sequestration and budgeting, deciding on the proper land use strategy andsuitable soil conservation practices. it ...

for evaluation of iranian onion morphotypes potentials and application of them in breedingprogrames, seeds of 23 iranian onion morphotypeswere collected from east azarbaijan (redazarshahrmorphotypes), tehran (red rey morphotypes), razavi khorasan (red neyshaboormorphotypes) and zanjan (gholyghese morphotypes). these onion morphotypes were planted inrcbd design in four replications in seed and p...

in a semiarid region of central iran, effects of parent materials, physiography and landscape position, land use, andmanagement practices on association of organic carbon with secondary (aggregates) particles and aggregate stability canhave important consequences in terms of carbon sequestration and budgeting, deciding on the proper land use strategy andsuitable soil conservation practices. it ...

results: participants’ concerns were classified into 4 main themes, including: inability, aging, isolation, and healthiness. conclusions: understanding these concerns might contribute to the enrichment of the existing literature by providing evidences from a different culture, assisting to design effective supportive strategies, planning training programs and appropriate infrastructures for wom...