Cellular damage or oxidative injury arising from free radicals or reactive oxygen species (ROS) now appears the fundamental mechanism underlying a number of human neurodegenerative disorder, diabetes, inflammation, viral infections, autoimmune pathologies and digestive system disorders. Free radicals are generated through normal metabolism of drugs, environmental chemicals and other xenobiotics...

A method by which small quantities (1-10 pg) of neurotransmitters can be injected into the blood supplying the brain of cephalopods has been used to produce conspicuous and instantaneous colour changes in the skin of the arms, head and body. Of the transmitter substances known to be present in the cephalopod brain, dopamine, noradrenalin and octopamine cause darkening when injected, acetylcholi...

BACKGROUND We aimed to compare hemodynamic and endocrine alterations caused by stress response due to Proseal laryngeal mask airway and endotracheal tube usage in laparoscopic cholecystectomy. MATERIALS AND METHODS Sixty-three ASA I-II patients scheduled for elective laparoscopic cholecystectomy were included in the study. Patients were randomly allocated into two groups of endotracheal tube ...

Amaç: Fibromyalji (FM) yeni tedavi aray›fllar›n›n sürdü¤ü önemli bir halk sa¤l›¤› sorunudur. Bu çal›flmada FM tedavisinde s›kl›kla kullan›lan trisiklik antidepresan amitriptilin ile henüz yeterince araflt›r›lmam›fl seçici noradrenalin geri al›m inhibitörü reboksetinin etkilerinin karfl›laflt›r›lmas› amaçlanm›flt›r. Ayr›ca noradrenalinin a¤r› duyumundaki mekanizmalarla iliflkisi bak›m›ndan, seçi...