نتایج جستجو برای: nuclear factor κ b nfκ b

تعداد نتایج: 1818504  

2014
Zheng Li Ya-Na Geng Jian-Dong Jiang Wei-Jia Kong

Oxidative stress and inflammation are proved to be critical for the pathogenesis of diabetes mellitus. Berberine (BBR) is a natural compound isolated from plants such as Coptis chinensis and Hydrastis canadensis and with multiple pharmacological activities. Recent studies showed that BBR had antioxidant and anti-inflammatory activities, which contributed in part to its efficacy against diabetes...

2013
Jia-sheng Wu Rong Shi Jie Zhong Xiong Lu Bing-liang Ma Tian-ming Wang Bin Zan Yue-ming Ma Neng-neng Cheng Fu-rong Qiu

In Chinese medicine, Xiexin decoction (XXD) has been used for the clinical treatment of diabetes for at least 1700 years. The present study was conducted to investigate the effective ingredients of XXD and their molecular mechanisms of antidiabetic nephropathy in rats. Rats with diabetes induced by high-fat diet and streptozotocin were treated with XXD extract for 12 weeks. XXD significantly im...

Journal: :Annals of the Rheumatic Diseases 2004

Journal: :Journal of the American College of Cardiology 2001

2013
Sheng-Hua Lu Ren-Yeong Huang Tz-Chong Chou

Periodontal disease characterized by alveolar bone resorption and bacterial pathogen-evoked inflammatory response has been believed to have an important impact on human oral health. The aim of this study was to evaluate whether magnolol, a main constituent of Magnolia officinalis, could inhibit the pathological features in ligature-induced periodontitis in rats and osteoclastogenesis. The steri...

2010
Kenneth H. Gabbay Kurt M. Bohren Roy Morello Terry Bertin Jeff Liu Peter Vogel Aileen B. Gordon Aileen B Gordon

1 To whom correspondence should be addressed: The Harry B. & Aileen B. Gordon Diabetes Research Center, 1102 Bates, Suite 550, MC 3-2353, Houston, TX 77030. Tel: 832-8243764; FAX: 832-825-3766. E-mail: [email protected] 2 Current address: Department of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205 3 The abbreviations used are: AR, aldose reductase...

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