نتایج جستجو برای: nutrient restriction

تعداد نتایج: 140869  

2013
Wilson C. Fok Yiqiang Zhang Adam B. Salmon Arunabh Bhattacharya Rakesh Gunda Dean Jones Walter Ward Kathleen Fisher Arlan Richardson Viviana I. Pérez

Because rapamycin, an inhibitor of the nutrient sensor mammalian target of rapamycin, and dietary restriction both increase life span of mice, it has been hypothesized that they act through similar mechanisms. To test this hypothesis, we compared various biological parameters in dietary restriction mice (40% food restriction) and mice fed rapamycin (14 ppm). Both treatments led to a significant...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Salvatore Fusco Cristian Ripoli Maria Vittoria Podda Sofia Chiatamone Ranieri Lucia Leone Gabriele Toietta Michael W McBurney Günther Schütz Antonella Riccio Claudio Grassi Tommaso Galeotti Giovambattista Pani

Calorie restriction delays brain senescence and prevents neurodegeneration, but critical regulators of these beneficial responses other than the NAD(+)-dependent histone deacetylase Sirtuin-1 (Sirt-1) are unknown. We report that effects of calorie restriction on neuronal plasticity, memory and social behavior are abolished in mice lacking cAMP responsive-element binding (CREB)-1 in the forebrai...

2018
H.C. Cunningham K.M. Cammack K.E. Hales H.C. Freetly A.K. Lindholm-Perry

Body weight response to periods of feed restriction and realimentation is critical and relevant to the agricultural industry. The purpose of this study was to evaluate differentially expressed genes identified in subcutaneous adipose tissue collected from cows divergent in body weight (BW) gain after feed restriction and realimentation. We compared adipose samples from cows with greater gain ba...

Journal: :Journal of animal science 2004
A N Scheaffer J S Caton D A Redmer L P Reynolds

Our objectives were to evaluate maternal body changes in response to dietary restriction or the increased nutrient requirement of fetal growth. In Exp. 1, 28 mature crossbred ewes (61.6 +/- 1.8 kg initial BW) were fed a pelleted forage-based diet to evaluate effects of pregnancy and nutrient restriction on visceral organ mass. Treatments were arranged in 2 x 3 factorially, with dietary restrict...

2015
Marianna Sadagurski Taylor Landeryou Gillian Cady Andrzej Bartke Ernesto Bernal-Mizrachi Richard A Miller

Transient nutrient restriction in the 3 weeks between birth and weaning (producing "crowded litter" or CL mice) leads to a significant increase in lifespan and is associated with permanent changes in energy homeostasis, leptin, and insulin sensitivity. Here, we show this brief period of early food restriction leads to permanent modulation of the arcuate nucleus of the hypothalamus (ARH), marked...

Journal: :Environmental pollution 1999
V H Smith G D Tilman J C Nekola

In the mid-1800s, the agricultural chemist Justus von Liebig demonstrated strong positive relationships between soil nutrient supplies and the growth yields of terrestrial plants, and it has since been found that freshwater and marine plants are equally responsive to nutrient inputs. Anthropogenic inputs of nutrients to the Earth's surface and atmosphere have increased greatly during the past t...

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