Reproduction is a complex, stepwise series of processes that begins with gametogenesis, continues through gamete interaction, implantation, embryonic development, growth, parturition, and postnatal adaptation, and is completed with the development and sexual maturation of the newly formed organism. These reproductive processes do not take place in a chemically pristine environment, but rather i...

4FRAME, Russell & Burch House, 96–98 North Sherwood Street, Nottingham NG1 4EE, UK; 5ECVAM, JRC Institute for Health and Consumer Protection, 21020 Ispra (VA), Italy; 6Institute for In Vitro Sciences, 21 Firstfield Road, Suite 220, Gaithersburg, MD 20878, USA; 728/30 Via Trieste, 21030 Brinzio (VA), Italy; 8Division of Carcinogenesis and Differentiation, FSII, 0240, German Cancer Research Centr...

a 19-year-old woman was referred to the emergency surgery department with severe abdominal pain, icterus, and anemia. the patient’s clinical and paraclinical findings in addition to her occupational and social history, convinced us to assay blood lead level (bll), which was 41/5 µg/dl. therefore toxicology consult was performed to treat lead toxicity. recheck of the bll showed the level as 53/7...

In a recent issue of the Asia Pacific Journal of Medical Toxicology (APJMT), the importance of empowering medical toxicology in the Asia Pacific Region has been discussed. In the editorial by Dr. Afshari, it has been stated that national societies of medical toxicology are important infrastructure for the development of medical toxicology, and the Asia Pacific Association of Medical Toxicology ...

1 Department of General Practice, Katholieke Universiteit Leuven, Comprehensive Cancer Institute Limburg, Limburg, Belgium. 2 Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, University of Birmingham, Birmingham, United Kingdom. 3 Department of Occupational and Environmental Medicine andPsychiatricEpidemiology, LundUniversity, Lund,Sweden. 4 Institute for Occupational...

Parkinson's disease (PD) is one of the neurodegenerative diseases which we can by certainty identify its pathology, however, this confidence disappeares when talking about the cause. A long history of trials, suggestions, and theories tried linking PD to a specific causation. In this paper, a new suggestion is trying to find its way, could it be toxicology? Can we-in the future-look to PD as an...

Division of Molecular Toxicology, IMM, Karolinska Institute, SE-171 77 Stockholm, Sweden [M. I-S., M. O.]; Department of Pharmacological Sciences, University of Newcastle upon Tyne Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom [A. K. D.]; Genetics Research Institute, Milan, Italy [S. G.]; and Environmental and Occupational Health Sciences Institute, University o...

Many potential neurotoxins exist and are classified (1-7) as: 1) pharmaceutical agents, 2) biological agents, 3) radiation and electricity, 4) heavy metals, 5) solvents and vapors, 6) insecticides, herbicides, fungicides, and rodenticides, 7) air pollution, 8) food additives, 9) social poisons. The reader is referred to sources of toxicology information available on the internet (6, 7). These i...

Background and Rationale The Office of Health Assessment and Translation (OHAT) of the Division of the National Toxicology Program (NTP) proposes to conduct a systematic review of the scientific evidence for health effects associated with occupational exposure to cancer chemotherapy agents. Cancer chemotherapy agents are cytotoxic drugs, and many of these agents are known mutagens and/or develo...

Goals and Scope The aim of the speciation symposia is to facilitate interdisciplinary and intersector discussion about all aspects of elements requiring an understanding of speciation, including" analytical science, geochemistry, biochemistry, clinical chemistry, environmental science, toxicology, essentiality and nutrition, medical uses, environmental and occupational health, and regulatory as...