6 Case study: Genome wide methylation and differential coverage between two conditions 12 6.1 Data Import and Preprocessing . . . . . . . . . . . . . . . . . . . 12 6.2 Coverage, methylation profiles and differential coverage . . . . . 13 6.3 Differential coverage: select significant windows . . . . . . . . . . 15 6.4 Merge frames . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 6.5...

in addition to graft clarity, an acceptable refractive error is essential to consider a corneal transplant successful. the most common complication of penetrating keratoplasty (pk) is postkeratoplasty astigmatism which can result in decreased visual acuity, anisometropia, and mono-ocular diplopia. these complications can cause patient dissatisfaction, in spite of a successful transplant. intrao...

purpose: controversy has recently risen about the presence of compensatory ocular countertorsion (coct) after head tilt. this study was performed to define the functional range of this phenomenon. methods: cycloplegic autorefraction was performed on 80 eyes with regular astigmatism 2d. objective autorefraction was performed in normal position, right and left head tilt positions of 5º, 10º, 15º,...

Pulsatile ocular blood flow, intraocular pressure, systemic blood pressure, and heart rate was measured in two groups of 15 patients. One received lignocaine 1.5 mgtkg intravenously prior to induction. There was a significant increase in intraocular pressure after suxamethonium, which was not associated with any rise in ocular blood flow. Both the IOP and ocular blood flow increased significant...

The performance of an infra-red analyser (Beckman LB-2) in sampling alveolar gas at ventilatory frequencies and volumes occuring in the human neonate has been examined. The optimum sampling flow rate was found to be 300 ml/min; at this flow the 90% response time of the analyser-catheter system was 140 ms. Correlation of estimated alveolar PCO2 and arterial PCO2 was performed in the rabbit which...

This article lists the theoretical criteria that need to be considered to assess the practicability of an automatic analyser. Two essential sets of criteria should be taken into account when selecting an automatic analyser: 'reliability' and 'practicability'. Practibility covers the features that provide information about the suitability of an analyser for specific working conditions.These prac...

The paper presents some models for optimizing the production rate of an automatic multitest blood analyser. A blood analysis may require one or more tests. The performance of the analyser depends on the test compositions of the analyses and the design of the analyser itself, The design can be changed. The optimal design can be determined by solving a set partitioning problem, given a representa...

Scalable Platform for Malicious Content Detection Integrating Machine Learning and Manual Review

The aim of this study was to determine whether objective ocular torsion in intermittent exotropia (IXT) changes after recession surgery, and to evaluate the relationship between change in ocular torsion and clinical parameters in IXT. Sixty patients between 3 and 14 years of age underwent lateral rectus (LR) recession for IXT. Digital fundus photographs were obtained from both eyes of each subj...