Purpose: Odontogenic cysts and tumors comprise a major component of lesions the oral maxillofacial region. The pathogenesis these involves interaction between odontogenic epithelium ectomesenchyme. However, clinical behavior biological entities is unpredictable. aim this study was to evaluate role Cyclooxygenase 2 (COX-2) in prognostication lesions.Material method: : In formalin-fixed paraffin-...

Odontogenic keratocyst (OKC) is a cyst of tooth origin with an aggressive clinical behavior including a high recurrence rate. It has been rechristened to Keratocystic odontogenic tumour (KCOT), as it better reflects its neoplastic nature. We report 2 contrasting cases of KCOT in association with impacted teeth and revisit the various treatment modalities used to tackle the aggressive nature and...

The orthokeratinized odontogenic cyst (OOC) is a rare developmental jaw cyst. Recognition of OOC as a unique entity has long been due, yet its inexplicable radiographic presentation resembling dentigerous cyst, histological likeness to odontogenic keratocyst (OKC) and inconsistent cytokeratin expression profiles overlapping with both as well as with the epidermis, makes it rather confounding. D...

An odontogenic keratocyst (OKC) and a giant cell granuloma (GCG) in the jaws are two well known entities, which have been reviewed extensively. However, the synchronous occurrence of these two lesions is exceptionally rare. We report a case of OKC exhibiting foci of CGC-like lesion.

Duchenne muscular dystrophy, a debilitating disease affecting male cIdldren, presents special considerations for the dentist faced with an oral-surgical problem. When general anesthesia is contraindicated, local anesthesia and a change in technique is indicated. One technique of outpatient surgical management of an odontogenic keratocyst, in a patient with Duchenne muscular dystrophy, is descri...

Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative, and nonodontogenic lesion whose etiology is not defined. Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. Central giant cell granuloma usually is an asymptomatic lesion, which may become evident during routine radiographic examination or as...

Background. The aim of this study was to investigate myofibroblast (MF) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of MFs and the clinical behavior of these lesions. Methods. A total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (UAM), solid ameloblastoma (SA), odontogenic keratocyst (OKC), dentigerous cyst (DC), rad...