T his paper reviews and analyzes various innovative Financing tech­ niques for highw ay and transit. W ith federal support d im inishing and transporta tion needs growing, agencies are seeking new ways to m eet this crisis. T he techniques discussed fall into the four broad categories of: (1) charges on benefiting properties; (2) jo in t ven ture approaches; (3) user charges; and (4) m arketing...

BACKGROUND The economic burden of diseases has become increasingly relevant to policy makers as healthcare expenditure keep rising in the face of limited and competing resources. Buruli ulcer (BU), a neglected but treatable tropical disease caused by Mycobacterium ulcerans, the only known environmental mycobacterium is capable of causing long term disability when left untreated. However, most B...

The condensation reaction of resorcinol with cis-[ClP(μ-N(t)Bu)(2)PN(H)(t)Bu] produced a difunctional derivative 1,3-C(6)H(4)[OP(μ-N(t)Bu)(2)PN(H)(t)Bu](2) (1), whereas the similar reaction with [ClP(μ-N(t)Bu)](2) resulted in the formation of a 1:1 mixture of dimeric and tetrameric species, [{P(μ-N(t)Bu)}(2){1,3-(O)(2)-C(6)H(4)}](2) (2a) and [{P(μ-N(t)Bu)}(2){1,3-(O)(2)-C(6)H(4)}](4) (2b), whic...

Busulphan (Bu) is an alkylating agent used in the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). Bu is extensively metabolized in the liver via conjugations with glutathione to form the intermediate metabolite (sulfonium ion) which subsequently is degraded to tetrahydrothiophene (THT). THT was reported to be oxidized forming THT-1-oxide that is further oxidized to...

Çağdaş sayılar kuramının en önemli açık problemlerinden birisi, verilen “aritmetik yönünden ilginç” bir F cisminin GF mutlak Galois grubunun ve bu grubun barındırdığı aritmetik yapının; Galois kuramı neticesinde, F cisminin ayrışabilir genişlemelerinin ve bu genişlemelerin aritmetik yapılarının; F taban cismine bağlı objeler cinsinden betimlenmesi problemidir. Bu problem, F’nin bir küresel (= g...

Optimal conditioning therapy for hematopoietic cell transplantation (HCT) in acute myelogenous leukemia (AML) remains undefined. We retrospectively compared outcomes of a consecutive series of 51 AML patients treated with oral busulfan (1 mg/kg every 6 hours for 4 days) and cyclophosphamide (60 mg/kg IV × 2 days) - (Bu/Cy) with 100 consecutive AML patients treated with pharmacokinetic targeted ...

In this paper, we propose a data mining-based approach to public bu er management in distributed database systems where database bu ers are organized into two areas: public and private. While the private bu er areas contain pages to be updated by particular users, the public bu er area contains pages shared among users from di erent sites. Di erent from traditional bu er management strategies w...