The cellular generation of toxic metabolites and subsequent detoxification failure can cause the uncontrolled accumulation of these metabolites in cells, leading to cellular dysfunction. Amyloid-beta protein (Abeta), a normal metabolite of neurons, tends to form toxic oligomeric structures that cause neurodegeneration. It is unclear how healthy neurons control the levels of intracellular oligom...

We present a new strategy, called dual-template docking oriented molecular imprinting (DTD-OMI), for facile and highly efficient imprinting within mesoporous materials. As compared with bulk imprinting, which is a widely used strategy, DTD-OMI did not require additional steps, but provided significantly improved imprinting efficiency and binding properties.

OMI/HIC is a point-to-point link technology under development. It has a exible packet format and supports ow control, which makes OMI/HIC usable as an alternative physical layer for other higher level protocols, like SCI and ATM. Routing chips with advanced routing strategies are made, and these routing chips are useful building blocks for larger switches for point to point links.

We present an algorithm for the retrieval of glyoxal from backscattered solar radiation, and apply it to spectra measured by the Ozone Monitoring Instrument (OMI). The algorithm is based on direct spectrum fitting, and adopts a two-step fitting routine to account for liquid water absorption. Previous studies have shown that glyoxal retrieval algorithms are highly sensitive to the position of th...

We present a new algorithm for the near-real time retrieval – within 3 h of the actual satellite measurement – of tropospheric NO2 columns from the Ozone Monitoring Instrument (OMI). The retrieval is based on the combined retrieval-assimilation-modelling approach developed at KNMI for off-line tropospheric NO2 from the GOME and SCIAMACHY satellite instruments. We have adapted the off-line syste...

Introduction The Netherlands are actively involved in atmospheric composition measurements from space since 1995 with measurements from the GOME, sCIAMAChY and OMI satellite instruments. The MetOp satellite series with GOME-2 onboard will continue these measurements until 2020, thereby providing an important global climate data record. KNMI plays an active and often leading role in the analysis...

Background Feature-tracking cardiovascular magnetic resonance (FTCMR) provides quantification of myocardial strain by analyzing cine MR images. A previous study has reported that CS measured by FT-CMR showed reasonable agreement with tagged MR in healthy volunteers. However, the usefulness of FT-CMR in patients with old myocardial infarction (OMI) has not been investigated. The purpose of this ...

Preface Background The Ozone Monitoring Instrument OMI is a Dutch-Finnish ozone monitoring instrument that will fly on NASA's Aura Mission, part of the Earth Observation System (EOS), scheduled for launch in January 2004. OMI's measurements of ozone columns and profiles, aerosols, clouds, surface UV irradiance, and the trace gases NO 2 , SO 2 , HCHO, BrO, and OClO fit well into Aura's mission g...

BACKGROUND Growth differentiation factor (GDF)-15, a divergent member of the transforming growth factor beta super-family does appear to be up-regulated in response to experimental pressure overload and progression of heart failure (HF). HF frequently develops after myocardial infarction (MI), contributing to worse outcome. The aim of this study is to assess the correlation between GDF-15 level...

We use a 2005–2009 record of isoprene emissions over Africa derived from Ozone Monitoring Instrument (OMI) satellite observations of formaldehyde (HCHO) to better understand the factors controlling isoprene emission in the continent and evaluate the impact on atmospheric composition. OMI-derived isoprene emissions show large seasonality over savannas driven by temperature and leaf area index (L...