Semenogelin (Sg) is secreted from the seminal vesicle and constitutes a major gel-forming protein in semen. Sg plays an important role for inhibiting sperm motility. Human seminal plasma has immunosuppressive effects on human peripheral blood lymphocytes (PBL). Here, we studied whether human Sg exerted immunosuppressive effects on human lymphocyte functions in vitro. We found that Sg reduced pr...

BACKGROUND Semenogelin (Sg), the main protein of human semen coagulum, prevents sperm capacitation. The objective of this study was to examine the role of Sg and its mechanism of action. METHODS AND RESULTS Sg blocked sperm capacitation triggered by various stimuli, via inhibition of superoxide anion (O(2)*-; luminescence assay) and nitric oxide (NO*; tested using diaminofluorescein) generati...

Introduction: Sensory Gating Inventory (SGI) measures behavioral aspects of Sensory Gating (SG). It is a filtering mechanism of brain that prevents irrelevant sensory inputs from entering into higher cortex information processing. It modifies sensitivity to sensory stimuli. Abnormal SG leads to overloading of information into cortex and brain dysfunction. Electrophysiological techniques cannot ...

This study was aimed to evaluate the effects of diets containing some hot and coldtemperament herb seeds according to Iranian traditional medicine (ITM) on some metabolicparameters in acute (24 h) and sub-acute (7 day) experiments that were performed on rats. Foreach experiment, effects of diets containing 10% herb seeds in category of hot (anise, fennel,ajowan) and cold (cucumber, watermelon, ...

The proteoglycan (PG), serglycin (SG), is expressed in several hematopoietic cells and studies of the SG knockout mice (SG -/) revealed prominent effects on the storage of certain mouse mast cell proteases (mMCPs) such as mMCP-4, -5 and -6. In this thesis, the role of SGPG during parasitic infection was addressed. Both SG +/+ and SG -/animals infected with Toxoplasma gondii had significantly el...

This experiment was carried out to evaluate the effect of specific gravity (SG) and particle size (PS) of Chromium-mordanated alfalfa neutral detergent fiber (NDF) markers on estimation of particulate rumen turnover. Thirty-two multiparous, mid lactation Holstein dairy cows (body weight=654±24 kg) were allotted to a completely randomized design experiment with two replications in a 4×4 factoria...

Aim—To evaluate the reliability of dipstick measurements of urine specific gravity (U-SG). Methods—Fresh urine specimens were tested for urine pH and osmolality (U-pH, U-Osm) by a pH meter and an osmometer, and for U-SG by three diVerent methods (refractometry, automatic readout of a dipstick (Clinitek-50), and (visual) change of colour of the dipstick). Results—The correlations between the vis...

Nina Antoniotti, RN, MBA, PhD [Chair, SG] Richard S. Bakalar, MD [SG] Norbert Belz, MHSA RHIA [WG] Leslie Bennett, LCSW [WG] Jordana Bernard, MBA [S] Anne Burdick, MD, MPH [Vice Chair, SG] David Brennan, MSBE [SG] Sharon Cain, MD [R] Lisa Carnahan, PhD [SG, WG] Jerry Cavallerano, PhD, OD [SG] Robert Cuyler, PhD [R] Veronica Decker, APRN, BC, MBA [WG] Kenneth Drude, PhD [R] Sara Gibson, MD [R] B...

SG (serglycin) PGs (proteoglycans) are strongly implicated in the assembly of MC (mast cell) granules. However, this notion has mainly been on the basis of studies of MCs of the connective tissue subtype, whereas the role of SG PG in mucosal MCs has not been explored. In the present study, we have addressed the latter issue by using mice with an inactivated SG gene. Bone marrow cells were diffe...

Retinoid-related orphan receptor (ROR)α4 is the major RORα isoform expressed in adipose tissues and liver. In this study we demonstrate that RORα-deficient staggerer mice (RORα(sg/sg)) fed with a high-fat diet (HFD) exhibited reduced adiposity and hepatic triglyceride levels compared with wild-type (WT) littermates and were resistant to the development of hepatic steatosis, adipose-associated i...