We report the optical imaging of a single atom with nanometer resolution using an adaptive optical alignment technique that is applicable to general optical microscopy. By decomposing the image of a single laser-cooled atom, we identify and correct optical aberrations in the system and realize an atomic position sensitivity of ≈ 0.5 nm/ √ Hz with a minimum uncertainty of 1.7 nm, allowing the di...

Since the discovery of X-rays, the use of imaging technology has continued to play an important role in medicine. Technological advancements have led to the development of various imaging modalities, most of which have been used to image organs deep within the human body. More recently, attention has focused on the application of imaging technology for evaluation of the skin. A variety of techn...

Optoacoustic imaging relies on the ultrasonic detection of pressure waves created after optical absorption. In this work we demonstrate imaging single red blood cells using an ultrasonic detection system at 200 and 400 MHz. ©2010 Optical Society of America OCIS codes: (170.3880) Medical and biological imaging; (350.0350) Other areas of optics

Developing diffuse optical tomography methods for neuroimaging of humans is challenging due geometry and light level constraints. Analysis of multi-distant high-density imaging arrays shows the feasibility of imaging up to 20 mm depth within the adult brain. ©2008 Optical Society of America OCIS codes: (170.6960) Tomography; (170.2655) Functional monitoring and imaging; (330.4270) Vision system...

We demonstrate a highly realistic model of optical coherence tomography, based on an existing model of coherent optical microscopes, which employs a full wave description of light. A defining feature of the model is the decoupling of the key functions of an optical coherence tomography system: sample illumination, light-sample interaction and the collection of light scattered by the sample. We ...

The limited resolution of a conventional optical imaging system stems from the fact that the fine feature information of an object is carried by evanescent waves, which exponentially decays in space and thus cannot reach the imaging plane. We introduce here an adiabatic lens, which utilizes a geometrically conformal surface to mediate the interference of slowly decompressed electromagnetic wave...

A non-invasive method for measuring the refractive index, extinction coefficient and film thickness of absorptive thin films using spectral-domain optical coherent tomography is proposed, analyzed and experimentally demonstrated. Such an optical system employing a normal-incident beam of light exhibits a high spatial resolution. There are no mechanical moving parts involved for the measurement ...

10.2 Physics Principles of In-line X-ray Phase-contrast Imaging......................................145 10.2.1 Attenuation, Phase Shift, and Optical Transmission ...................................145 10.2.2 System Configuration of In-line Phase-contrast Imaging............................145 10.2.3 Theoretical Framework of In-line Phase-contrast Imaging with Ideal Imaging Systems ...............