BACKGROUND & OBJECTIVES Suppurative oral and maxillofacial infections are usually mixed infections due to aerobic and anaerobic bacteria, most frequently by oral streptococci and antimicrobial treatment is necessary for such infections. The aim of this study was to investigate the antimicrobial susceptibility of Streptococcus mitis group strains isolated from Romanian patients with different or...

OBJECTIVES We sought to determine whether taking oral erythromycin prior to SPECT myocardial perfusion imaging with Tc99m-sestamibi would reduce the amount of interfering extra-cardiac activity and improve the image quality. METHODS A total of 96 patients who were routinely referred for myocardial perfusion imaging were randomly assigned to one of two groups. Patients in group A received 500 ...

1/M Acne conglobata 8 to 0 0.25 60.5 8.1 None None Elevated serum cholesterol, creatinine kinase at last visit, mild cheilitis 2/M Acne fulminans 8 to 2 0.18 55.5 10.0 Oral methylpred nisolone Adapalene gel Transient elevation of serum TG, mild cheilitis 3/F Acne fulminans 8 to 4 0.15 34.8 7.4 Oral prednisolone Clindamycin/ benzoyl-peroxide Transient elevation of serum cholesterol, γ-GT, TG, mi...

BACKGROUND Hypersensitivity reactions to metronidazole are infrequently described. However, we believe that such reactions are increasing due to growing use of the drug for the treatment of amebiasis and anaerobe infections combined with other antibiotics. The present study assesses the need for oral provocation in patients with probable hypersensitivity reactions to metronidazole. METHODS We...

Acne vulgaris is a common disease of the pilosebaceous unit and affects adolescents and adults. Because high-quality guidelines regarding treatment of acne in pregnancy are scarce, management of this condition can be challenging. We describe the safety profile of common therapies and outline approaches based on available evidence. Topical azelaic acid or benzoyl peroxide can be recommended as b...

In vitro Ro 15-8074 and Ro 19-5247 (T2525), two new oral cephalosporins, were active against 410 penicillin-susceptible and -resistant isolates of Neisseria gonorrhoeae. Two new macrolides, A-56268 and to a lesser extent roxithromycin (RU 28965), were active against Chlamydia trachomatis. A-56268 had activity against N. gonorrhoeae similar to that of erythromycin.