Thyroid gland metastatic tumors are rare in clinical practice. Clear cell RCC is one of common metastatic tumors to thyroid. We here reported a case of incidentally found clear cell renal carcinoma metastasis to the thyroid gland 3 years after nephrectomy, in the thyroidectomy procedure performed for the patient due to the thyroid enlargement caused by multinodular goiter. A 65-year-old Iranian...

Oral region metastasis of hepatocellular carcinoma (HCC), the most common primary tumor of the liver, is rare and may occur in the mandibular body region. We present here a rare and interesting case of HCC metastasis to the mandibular condyle without any other extrahepatic metastatic sites of a 59-year-old man. This finding suggest that incidental extrahepatic lesions in the more uncommon sites...

Sunitinib is an oral inhibitor of tyrosine kinases, including vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR), and has been associated with higher response rates and longer progression-free survival in patients with metastatic renal cell carcinoma (RCC) as compared with interferon [1]. We describe a long-term remission from recent-onset ty...

Objective: To document cervical node metastasis in oral squamous cell carcinoma (OSCC) of buccal mucosa and analyze the oncological necessity most suitable neck dissection, population a tertiary care hospital.
 Study Design: Descriptive cross-sectional study.
 Place Duration Study: Maxillofacial department, Abbasi Shaheed Hospital, Karachi Pakistan, from Jul 2018 to 2020.
 Method...

Oral squamous cell carcinoma has high chances of cervical lymph node metastasis. This case series describes the distribution of cervical lymph nodes in 50 cases of squamous cell carcinoma of tongue and floor of mouth. The mean age was 47.28±10.5 years. Thirty positive metastatic lymph nodes were found; 90% occurring at level I-II mostly in T4 size but also in T1 and T2 cases. The distribution o...

background: oral cancer is among the 10 most common cancers worldwide with an increasing global incidence. compromised antioxidant defense system plays a role in occurrence of cancer. this study evaluated the salivary antioxidant level of oral cancer patients compared to a control group. patients and methods: this case-control study was conducted on 22 oral squamous cell carcinoma patients pres...

abstract background and aim: oral cancer is one of the most common cancers of the head and neck. considering the high prevalence and mortality percentage of oral cancer and the significant advances in immunology and identification of different cytokines, the aim of the present study was to compare the concentration of il8 in saliva of patients with oral squamous cell carcinoma (oscc) and health...

metastatic tumors account for 1% of all oral malignancies. metastasis to jaw bones is common, particularly in the mandible, rare in the oral soft tissues, and account for only 0.1% of oral malignancies. the majority of metastatic cases (70%) reported in the literature have primary tumors located in the lung, breast, kidney, and colon. metastasis is a biological complex process that involves det...

Introduction: Oral tumors are one of the most challenging tumors regarding their good prognosis if diagnosed early and very difficult to control in advancing stages. Objectives: To study the prevalence, histopathological types and clinical presentation of various malignant oral tumors and their precursor lesions. Materials and Methods: This study includes the analysis of oral tumors received in...

The present study conducted an immunohistochemical investigation of cyclin D1 and Ki-67 expression in oral squamous cell carcinoma (SCC) to evaluate the correlations between cell differentiation, cell proliferation and metastasis, and the effect of anticancer drug medication and cyclin D1 expression. Cyclin D1 and Ki-67 were detected clearly in the nuclei of 35 SCC samples. No correlation betwe...