Background: A number of conditions demands first trimester abortions including medical and social causes. This study was mainly undertaken in order to compare the oral misoprostol with intramuscular carboprost for cervical ripening suction evacuation termination pregnancy up 12 weeks gestation. Material methods: randomized controlled trial determine safety efficacy over ripening. total 120 preg...

background: we sought to compare the effectiveness and safety of sublingual versus vaginal misoprostol for the termination of pregnancy with a live full-term fetus. methods: this randomized, triple-blind, placebo-controlled clinical trial was performed on 200 primiparous women with normal, singleton, full-term pregnancies candidated for the induction of labor. sublingual and vaginal tablets con...

Introduction: This study was conducted to evaluate the efficacy of 800µg vaginal misoprostol after wetting alkaline PH vagina with 3% acetic acid in comparison with 800µg vaginal misoprostol alone in the alkaline PH vagina in terminating first trimester pregnancies. Methods: In this clinical trial, a total of 100 healthy women between 20 and 40 years old requesting legal terminat...

BACKGROUND Letrozole is a third-generation selective aromatase inhibitor. Animal data suggested that it might be useful in medical abortion. We performed two pilot studies to assess the feasibility of using letrozole in combination with either mifepristone or misoprostol for termination of pregnancy up to 63 days. STUDY DESIGN We recruited 40 subjects who requested legal termination of pregna...

BACKGROUND This study aims to assess the efficacy of a combination of mifepristone and misoprostol in the management of missed miscarriage and anembryonic pregnancy. METHODS Data of 220 consecutive women with miscarriage, undergoing medical evacuation of the uterus were collected prospectively at an early pregnancy assessment unit in a tertiary referral hospital. Each woman received a single ...

BACKGROUND AND METHODOLOGY South Africa's Choice on Termination of Pregnancy Act of 1996 provides for safe termination of pregnancy (TOP) in designated facilities in the public and private health sectors. In 2001, mifepristone-misoprostol medical abortion was approved for TOP up to 56 days, but this method is not yet available in the public sector. Information on the operational requirements fo...