Probably the greatest challenge to those managing patients with oral diseases is the dilemma of attempting to predict which oral erythroplakias, leukoplakias, lichenoid and other potentially malignant mucosal disease (PMD) such as oral submucous fibrosis will progress to neoplasia--notably oral squamous cell carcinoma (OSCC). The paper reviews progress over the past decade and the application t...

BACKGROUND: Oral Submucous Fibrosis (OSMF) is a chronic, insidious, scarring disease of the mouth often involving palate, oro-pharynx, pharynx, esophagus, tongue and buccal mucosa which leads to ulceration, blanching ultimately limited opening. The aim study describe age, gender district-wise distribution oral submucous fibrosis cases assess malignant transformation rate among patients with who...

background: syndecan‑1 is abundant in normal tissues and reduced in squamous cell carcinomas. leukoplakia and oral submucous fibrosis (osf) are oral pre‑cancerous disorders that have potential for malignant transformation. the aim of this study was to evaluate the expression of syndecan‑1 in leukoplakia and osf and to identify its role as a reliable marker for predicting malignant changes. mate...

Oral sub mucous fibrosis is a crippling disease of mouth with high malignant potential that has high prevalence rate in India and South East Asia. The treatment of patients with oral submucous fibrosis depends on the degree of clinical involvement. If the disease is detected at a very early stage, cessation of the habit is sufficient. Medical treatment is symptomatic and predominantly aimed at ...

Background and PurPose: The three most common causes of trismus are oral submucous fibrosis, orofacial gangrene in malnourished children and cancers of the head and neck. 2 Very often, they share the same triad: fibrosis of the soft tissue of the cheek, masticatory muscles and osseous overgrowth. In severe cases, this will eventually lead to severe pain, weight loss and poor oral hygiene. 4, 5

Back ground: On the Indian subcontinent, the use of smokeless tobacco in various forms is very popular. Oral submucous fibrosis is a chronic condition of the oral mucosa, which results in a marked rigidity with progressive inability to open the mouth and has an increased risk of undergoing carcinomatous changes about four to eight percent. Objectives: The objective of this study was to evaluate...