A 39-year-old woman presented with a 6-week history of an ulcerated and indurated lesion in the upper lip (Fig. 1). The histological study showed an ulcer with dense lymphoplasmacytic infiltrate and the immunohistochemistry (IHC) was positive for spirochetes. Both, the rapid plasma reagin test (RPR) and the microhemaglutination of the Treponema pallidum (MHA-TP) test were reactive with a RPR of...

Tuberculosis is a chronic infectious disease affecting humans of all ages in all parts of the world. The primary site of infection commonly involves lungs, although it can affect any part of the body, including oral cavity. Although oral manifestations of tuberculosis are very rare, the disease can present itself in a variety of clinical appearances which may mimic malignancy clinically. Thus t...

Tuberculosis is a chronic infectious disease that can affect any part of the body, including the mouth. An upsurge in the number of tuberculosis cases, with a strong association with HIV infection, has been noted. We present a case of tuberculosis that clinically resembles a malignant chronic ulcer in the retromolar trigone-an uncommon site of occurrence. Histologically, the case demonstrated a...

tuberculosis is a major cause of morbidity and mortality worldwide. it is a chronic granulomatous disease that can affect any part of the body, including the oral cavity. oral lesions of tuberculosis, though uncommon, are seen in both the primary and secondary stages of the disease. this article presents a case of tuberculosis of the buccal mucosa, manifesting as non-healing, non-painful ulcer....

Oral ulcers are diverse in number. Recurrent aphthous ulceration is the most common form of painful ulcerations in oral cavity. The diagnosis is well defined but the etiology and pathogenesis remains unclear. It is common condition affecting 20% of general population. This review article provides the exact etiology, diagnosis, criteria and treatment of RAS.

BACKGROUND Peptic ulcer is the most common cause of upper gastrointestinal bleeding (GIB) and nutritional support is a helpful strategy in malnutrition prevention during treatment. As early oral feeding in patients with GIB may shorten hospital stay and decrease costs and risk of infection, the present study was carried out to investigate the effects of early oral feeding on relapse and symptom...

OBJECTIVE To present 2 cases of Epstein-Barr virus (EBV)-positive mucocutaneous ulcer of the oral mucosa in association with human immunodeficiency virus infection. STUDY DESIGN Two recently diagnosed cases of EBV-positive mucocutaneous ulcer of the oral mucosa in patients with human immunodeficiency virus (HIV) were reviewed with regard to their clinical, histomorphologic, and immunophenotyp...

Sodium polyacrylate (PANa) is a water-soluble, high-molecular compound, and its aqueous solution shows a very high viscosity and stringiness. In the present study, preventive effects of PANa on three kinds of esophageal lesions induced by gastric juice were examined in comparison with those of aceglutamide aluminum and sodium alginate. The influences of PANa on gastric contents were also studie...

AIMS To determine risk factors for peptic ulcer bleeding other than non-steroidal anti-inflammatory drugs (NSAIDs). Methods-Data on possible antecedent risk factors obtained in a large case control study of 1121 patients admitted to hospitals in Glasgow, Newcastle, Nottingham, Oxford, and Portsmouth with bleeding peptic ulcers were compared with the same information obtained in 989 population c...

Background/Aims: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by decreased salivary and lacrimal gland secretions. B-cell abnormalities have been identified in pSS. We tested the leptin (LP) and leptin receptor (LR) levels in pSS and to analyze relationship between their levels and clinical manifestation of pSS. Methods: We assayed LP and LPR levels measured b...