The desire of improved palatability in orally administered products has prompted the development of numerous formulations with improved performance and acceptability. Orally disintegrating tablets are an emerging trend in novel drug delivery system and have received ever-increasing demand during the last few decades. The field has become a rapidly growing area in the pharmaceutical industry and...

We previously prepared and pharmaceutically evaluated ginger orally disintegrating (OD) tablets, optimized the base formulation, and carried out a clinical trial in healthy adults in their 20 s and 50s to measure their effect on salivary substance P (SP) level and improved swallowing function. In this study, we conducted clinical trials using the ginger OD tablets in older people to clinically ...

Sir: Olanzapine is a thienobenzodiazepine antipsychotic that has a broad in vitro affinity for several receptors, including serotonergic, cholinergic, dopaminergic, and adrenergic receptors. Olanzapine is approved for treatment of psychoses at doses up to 20 mg/day. New research suggests benefits of higher doses of olanzapine. Anecdotal case reports highlight the benefits of olanzapine at 50 mg...

 Severe Renal or Hepatic Impairment in Adults: Use a lower starting dose of 0.5 mg twice daily. May increase to dosages above 1.5 mg twice daily at intervals of at least one week. (2.4)  Oral Solution: Can be administered directly from calibrated pipette or mixed with beverage (water, coffee, orange juice, or low-fat milk). (2.6)  M-TAB Orally Disintegrating Tablets: Open the blister only wh...

Since orally disintegrating tablets (ODTs) of tramadol hydrochloride are not available in the market, so an attempt has been taken to formulate and evaluate ODT preparation hydrochloride. In this present work, direct compression was technique used for preparing using superdisintegrants like croscarmellose sodium, sodium starch glycolate crospovidone at different concentrations. Prepared formula...

Lamotrigine (LMG) is an Antiepileptic drug which is widely used in epilepsy. It is also used in simple and complex partial seizures and secondary generalized tonic-clonic seizures. It is poorly water soluble drug (0.17mg/ml at 25 0 C). Thus, in the work under taken, an attempt was made to enhance the water solubility by complexation with β-cyclodextrin (1:5 molar ratios). The mouth dissolving t...

Orally disintegratingtablets (ODTs) comprising sustained release (SR) coated microparticles smallerthan 250 µm provide an appealing dosage form for patients with dysphagia,offering a superior mouthfeel and highly convenient route of administrationwithout the need water. SR coating requisite size(<200 µm) is incredibly challenging however utilisation theMicroCoat™ techno...