The interaction of mycophenolate mofetil (MMF) with ferrous ions (Fe(2+)) in the solid state, in water, and in polar organic solvents was investigated using (1)H-NMR, (13)C-NMR, IR, and UV-visible (Vis) spectroscopies. A red-purple colored substance was formed after grinding solid MMF and FeSO4·7H2O in a mortar. The IR spectrum of taken as a KBr tablet of the colored substance showed a new abso...

This study compares three groups of murderers: those who have received a death sentence (n = 18), those who were eligible to receive a death sentence but did not have it sought against them (n = 18), and those who were not eligible for the death penalty (n = 18). A retrospective record review of these 54 pretrial detainees in South Carolina who underwent court-ordered competency and criminal re...

In vitro dissolution methodologies that adequately capture the oral bioperformance of solid dosage forms are critical tools needed to aid formulation development. Such methodologies must encompass important physiological parameters and be designed with drug properties in mind. Two-phase dissolution apparatuses, which contain an aqueous phase in which the drug dissolves (representing the dissolu...

Natural montmorillonite was modified with a quaternary ammonium compound, hexadecyltrimethylammonium (HDTMA). The sedimentation capabilities of unmodified and modified montmorillonites were then investigated. The sedimentation velocity of modified montmorillonites increased if the amounts of adsorbed HDTMA were from 0.3 to 1.0 times the cation exchange capacitity (CEC). It also emerged that the...

OBJECTIVE To describe trends in hospitalizations with a diagnosis of substance abuse among reproductive-age women from 1998-2003. METHODS Data were obtained from the Healthcare Cost and Utilization Project Nationwide Inpatient Sample. Hospitalizations with a diagnosis of substance abuse were categorized into subgroups by age, primary expected payer, substance-specific diagnoses, concomitance,...

Substance dependency has been related to an impairment in executive functions and to a dysfunction of the frontal cortex. In this study we developed two experimental tasks, which are physically identical, to analyze whether substance-dependent individuals are impaired in shifting response patterns (stimulus response links) or preferences (stimulus outcome links). To increase the specificity of ...

Adrenergic nerve fibres of the mammalian uterus degenerate during pregnancy. The behaviour of peptidergic fibres, such as substance P-positive fibres and of its preferred neurokinin 1 receptor (NK1-R), is poorly studied in the pregnant rat uterus. The present study analysed the changes in substance P immunoreactivity and in the expression of NK1-R protein in the uterus of non-pregnant, pregnant...

In a previous paper (Hare, Wildy, Billett, and Twort, 1952) a scheme employing fermentation of carbohydrates and organic acids was put forward for the classification into six groups of the anaerobic cocci derived from human beings. There is at present extremely little information as to the occurrence of anaerobic cocci on the mucous and skin surfaces of normal human beings. This, together with ...

Microalgae contain valuable compounds that can be harnessed for industrial applications. Lignocellulose biomass is a plant material containing in abundance organic substances such as carbohydrates, phenolics, organic acids and other secondary compounds. As growth of microalgae on organic substances was confirmed during heterotrophic and mixotrophic cultivation, lignocellulose derived compounds ...