Hydrogen bond donor catalysis represents a rapidly growing subfield of organocatalysis. While traditional hydrogen bond donors containing N-H and O-H moieties have been effectively used for electrophile activation, activation based on other types of non-covalent interactions is less common. This mini review highlights recent progress in developing and exploring new organic catalysts for electro...

The direct β-activation of saturated aldehydes and ketones has long been an elusive transformation. We found that photoredox catalysis in combination with organocatalysis can lead to the transient generation of 5π-electron β-enaminyl radicals from ketones and aldehydes that rapidly couple with cyano-substituted aryl rings at the carbonyl β-position. This mode of activation is suitable for a bro...

Within the realm of catalytic asymmetric hydrogenation, the focus continues to be on the use of chiral metal complexes in conjunction with a hydrogen source. Recently, the widespread development of organocatalysis, including the invention of iminium activation, has led to the discovery of many new enantioselective transformations. Based on this strategy, a number of bioinspired processes for th...

In the last ten years organocatalysis has emerged as an efficient and sustainable strategy for the asymmetric synthesis of chiral molecules. Optically active intermediates for novel interesting transformations are generated under mild and operationally simple conditions when selenium-containing compounds are used as reaction partners. The peculiar reactivity of organoselenium compounds has been...

Organocatalysis has evolved into an effective complement to metal- or enzyme-based catalysis in polymerization, polymer functionalization, and depolymerization. The ease of removal greater sustainability organocatalysts relative transition-metal-based ones spurred development specialty applications, e.g., medical devices, drug delivery, optoelectronics. Despite this, the use organocatalysis oth...

The recent advances in asymmetric organocatalysis using eutectic mixtures as a reaction medium are revised this mini-review. In addition, the first enantioselective transformations chiral solvents, which play role of green and organocatalyst, described. minireview we intend to deepen not only synthetic aspects mixtures, but also fundamental issues that seem be essential for successful developme...