In my series of total hip replacement, the cemented Ceraver Osteal endoprostheses was used since 1977 in 150 cases, the titanium uncemented screw cup ring with a ceramic core since 1985 in 131 cases and since 1996 a pressfit titanium cup with a pure titanium fibre mesh with ceramic core in 30 cases. The ceramic head was fixed to the stem in all cases through conical sleeving. The titanium femor...

Hydromorphone is a semi-synthetic μ-agonist commercially available in oral, rectal and injectable formulations for the control of acute and chronic pain [1]. Hydromorphone is typically used for moderate-to-severe pain, and is an effective alternative to morphine [1]. Like other μ-agonists in the opioid family there is no ceiling effect for hydromorphone, and cross-tolerance with other opioids i...

The aim of the present study was to design and evaluate a chronomodulated time-clock pulsatile tablets of valsartan to release it after a certain lag time, independent of the gastrointestinal pH, in its absorption window to cope with the circadian rhythm of human body for blood pressure elevation. Core tablets were prepared by direct compression of a homogenous mixture of valsartan, Avicel PH10...

A dry process induced phase transited, non disintegrating, controlled release, in situ formed asymmetric membrane capsular system for poorly water soluble drug, ketoprofen, was developed and evaluated both in vitro and in vivo for osmotic and controlled release of the drug. In situ formed asymmetric membrane capsules were prepared using fabricated glass capsule holders via dry, phase inversion ...

This paper presents a Collaborative Project Based Learning model using Tablet PCs to enhance the design components in engineering classroom instruction. The core of our proposed model is to incorporate small in-class Tablet PC-based collaborative design projects to reinforce theory with design examples and to guide students through the design process. This PBL model has been implementation in t...

BACKGROUND Orally available ticagrelor in combination with low-dose aspirin (75-100 mg/day) is indicated for adult patients with acute coronary syndromes. However, patients with swallowing difficulties may be unable to consume the currently available 90-mg tablet. It is hypothesized that ticagrelor could be given to this patient cohort as a crushed dose administered either orally or via a naso-...

We present an innovative drawing tool that can detect tangible drawing instruments on a capacitive multi-touch tablet. There are three core components to the system: the tangible hardware, the recognizer used to identify the tangibles, and the drawing application. Our tangible drawing instruments include a ruler, protractor and set square. Users can apply these familiar physical instruments to ...

The aim of present investigation was to develop press coated tablet for pulsatile drug delivery of ketoprofen using hydrophilic and hydrophobic polymers. The drug delivery system was designed to deliver the drug at such a time when it could be most needful to patient of rheumatoid arthritis. The press coated tablets containing ketoprofen in the inner core was formulated with an outer shell by d...

In the present study, magnetic core-shell manganese ferrite nanoparticles (MCMNP) were synthesized and used for construction of a magnetic core-shell manganese ferrite nanoparticles modified screen-printed carbon electrode (MCSNP-SPCE). Cyclic voltammetry was used to study the electrochemical behavior of chlorpromazine (CPZ) and its determination was conducted by applying square wave voltammetr...

distribution of water vapor in the atmosphere of the room poultry houses is usually an effective and economical solution to reduce heat stress of the chickens. experimental studies were conducted in a small saloon located in the farm machinery department of shiraz university. the rotary cup fogging system consisted of a cup which was derived by dc motor. rotational speed of the cup caused the w...