نتایج جستجو برای: osteonectin
تعداد نتایج: 642 فیلتر نتایج به سال:
HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage.
Human bone marrow mesenchymal stem cells (MSC) are pleiotropic cells that differentiate to either adipocytes or osteoblasts as a result of cross-talk by specific signaling pathways including heme oxygenase (HO)-1/-2 expression. We examined the effect of inducers of HO-1 expression and inhibitors of HO activity on MSC differentiation to the osteoblast and adipocyte lineage. HO-1 expression is in...
Vitamin C and vitamin E are known as important cellular antioxidants and are involved in several other non-antioxidant processes. Generally vitamin C and vitamin E are not synthesized by humans and therefore have to be applied by nutrition. The absence or deficiency of the vitamins can lead to several dysfunctions and even diseases (e.g. scurvy). The main interest in this study is that vitamin ...
STUDY DESIGN An external compression model was used to evaluate gene and protein expression in intervertebral discs with moderate disc degeneration. OBJECTIVE To determine messenger ribonucleic acid and protein expression levels of relevant disc components. SUMMARY OF BACKGROUND DATA An animal model of mechanically induced disc degeneration was developed and characterized histologically. Ho...
PURPOSE To investigate the proportion of breast cancers arising in patients with germ line BRCA1 and BRCA2 mutations expressing basal markers and developing predictive tests for identification of high-risk patients. EXPERIMENTAL DESIGN Histopathologic material from 182 tumors in BRCA1 mutation carriers, 63 BRCA2 carriers, and 109 controls, collected as part of the international Breast Cancer ...
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