Purpose To evaluate the relationship between the IOP-lowering effect of trabodenoson and the associated structural and functional changes in the trabecular meshwork (TM). Methods Six independent cohorts of young and aged mice were exposed to three different topical once-a-day formulations of trabodenoson and eyes were compared to those treated with placebo drops. IOP was measured daily just b...

We consider dissipative effects occurring in the optically thick inner parts of the rela-tivistic outflows producing gamma-ray bursts and X-ray flashes, emphasizing specially the Comptonization of the thermal radiation flux that is advected from the base of the outflow. Such dissipative effects –e.g. from magnetic reconnection, neutron decay or shocks – would boost the energy density of the the...

The anterior chamber angle is the actual anatomical angle created by the root of the iris and the peripheral corneal vault. Within it lie the structures involved in the outflow passage of the aqueous, namely the trabecular meshwork and the Schlemm’s canal (figure 1). The depth of the angle in a healthy eye is approximately 30°, with the superior part usually less deep than the inferior half. Ho...

Vegetation has closer relationship with the hydrological cycle, changing them due to their conditions. Vegetation regulates the hydrological cycle making water faces all the stages adequately causing the process stability. Vegetation retains great parcel of the rainwater, freeing it for the water courses and surface and subterranean reservoirs, little by little. In this work, the impact of defo...

In this paper we propose the analysis of the incompressible nonhomogeneous Navier-Stokes equations with nonlinear outflow boundary condition. This kind of boundary condition appears to be, in some situations, a useful way to perform numerical computations of the solution to the unsteady Navier-Stokes equations when the Dirichlet data are not given explicitly by the physical context on a part of...

Thunderstorm case studies and earlier observations are described which illuminate the relationship between cloud vertical development and the prevalence of intracloud (IC) and cloud-to-ground (CG) lightning. A consistent temporal evolution starting with peak IC activity changing to predominant CG activity and concluding with strong outflow (microburst) suggests that ice is responsible for both ...

The present paper studies a discrete-time storage process with discrete states. This model has the inflow which is defined as independent random variables with a common negative binomial distribution and has the certain outflow discipline. Reversibility and quasi-reversibility for the process are investigated and the reversible measure is given. And thus, under a certain condition, it is shown ...

PURPOSE To study the effect on outflow facility and outflow resistance of a nitinol microstent implanted into Schlemm's canal. METHODS Using a constant pressure perfusion method, outflow facility and outflow resistance were measured in 26 pairs of dissected anterior segments from donated human eyes. Measurements were made at perfusion pressures of 10, 20, 30 and 40 mm Hg. The Hydrus Microsten...