نتایج جستجو برای: ovar

تعداد نتایج: 125  

2006
Beloo Mirakhur Hemant K. Parekh Henry Simpkins

Many mechanisms have been proposed to explain cisplatin resistance, suggesting that this phenomenon is multifactorial. In an attempt to define the chromosome(s) responsible for cisplatin resistance in the human ovar ian carcinoma 2008/C13* cell lines, somatic cell hybrids were obtained following fusion of the cisplatin-resistant 2008/C13* cells with an A9 rodent fibroblast cell line. The hybrid...

2016
David J. Pulford Philipp Harter Anne Floquet Catherine Barrett Dong Hoon Suh Michael Friedlander José Angel Arranz Kosei Hasegawa Hiroomi Tada Peter Vuylsteke Mansoor R. Mirza Nicoletta Donadello Giovanni Scambia Toby Johnson Charles Cox John K. Chan Martin Imhof Thomas J. Herzog Paula Calvert Pauline Wimberger Dominique Berton-Rigaud Myong Cheol Lim Gabriele Elser Chun-Fang Xu Andreas du Bois

BACKGROUND The focus on translational research in clinical trials has the potential to generate clinically relevant genetic data that could have importance to patients. This raises challenging questions about communicating relevant genetic research results to individual patients. METHODS An exploratory pharmacogenetic analysis was conducted in the international ovarian cancer phase III trial,...

Journal: :Journal of vestibular research : equilibrium & orientation 1993
D M Merfeld L R Young C M Oman M J Shelhamer

A "sensory conflict" model of spatial orientation was developed. This mathematical model was based on concepts derived from observer theory, optimal observer theory, and the mathematical properties of coordinate rotations. The primary hypothesis is that the central nervous system of the squirrel monkey incorporates information about body dynamics and sensory dynamics to develop an internal mode...

Journal: :Physiological genomics 2007
Orla M Keane Ken G Dodds Allan M Crawford John C McEwan

Gastrointestinal nematodes are a major cause of disease in grazing livestock; however, individual animals differ in their response to infection. To identify genes whose expression correlates with resistance status, transcriptional profiling of resistant and susceptible sheep was undertaken. Transcription profiles were taken at three time points during the growth of lambs. The number of genes di...

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