In aerobic bioprocesses, oxygen is a key substrate; due to its low solubility in broths (aqueous solutions), a continuous supply is needed. The oxygen transfer rate (OTR) must be known, and if possible predicted to achieve an optimum design operation and scale-up of bioreactors. Many studies have been conducted to enhance the efficiency of oxygen transfer. The dissolved oxygen concentration in ...

In this work, numerical and experimental analyses of a double-pipe heat exchanger with SiO2 nanoparticles were performed. The study was conducted by using the k-e turbulence model Galerkin weighted residual finite element method. nanofluid used in inner pipe at various solid particle volume fractions. Effects flow rate temperature on overall transfer coefficient examined. Brownian motion effect...

Bubble columns (with and without suspended solids) have been used widely as chemical reactors, bioreactors and equipment for waste water treatment. The key design parameters in bubble columns are: • gas holdup; • gas-liquid interfacial area; • volumetric liquid-phase mass transfer coefficient; • gas and liquid axial dispersion coefficients; Despite the large amount of studies devoted to hydrody...

In this article, stream flow effectivness is based on hydraulic network studied in the shell-side of a shell and tube heat exchange as a case study. For an appropriate heat exchangers rating design to meet a specified duty, it's better to consider each stream flow separately. Using the hydraulic network principals, a set of the correlations for calculating different stream flow rates in the cro...