An ultrasonic Doppler was used to monitor embolic activity in the arterial line of an extracorporeal circuit. No differences in embolic activity were observed when either 100% N2 or 95% Oz-5% C02 gases were swept through a bubble oxygenator. Information is presented suggesting that nitrogen or air micro emboli are more deleterious than oxygen or carbogen microemboli. Consequently, this article ...

Background: During veno-venous extracorporeal membrane oxygenation (VV-ECMO), systemic anticoagulation is required to prevent thrombotic complications within the circuit and oxygenator. The unfractionated heparin (UFH) commonly administered as a standard anticoagulant, but in our institute recombinant human thrombomodulin (rhTM), instead of UFH, used an anticoagulant for VV-ECMO. In present stu...

Pmc 2: 1419, Dec 1971 6 Kolobow T, Spragg RG, Pierce JE, et al: Extended term (to 16 days) partial extracorporeal blood gas exchange with the spiral membrane lung in unanesthetized lambs. ASAIO 17:350, 1971 7 Bartlett RH, Noyes BS, Drinker PA: Development of a membrane oxygenator: Overcoming blood diffusion limitation. J Thorac Cardiovasc Surg 58:795, December 1969 8 Land6 AJ. Edwards L, Bloch ...

As obesity increases in prevalence, so will cases in which patients present at the boundaries of care. We report the support of a class III obese man, having a body mass index of 60.8 kg/m2 and in acute renal failure, with a single Trillium-coated Affinity NT Hollow Fiber oxygenator in cardiopulmonary bypass for an emergent aortic valve replacement secondary to infective endocarditis. A maximum...

PurposeCurrent commercially available EVLP solutions are designed to mimic physiological conditions support donor lungs outside of the human body. These have been effective at offering for donated after brain death but they limited in their ability cardiac death. To characterize hemodynamics utilizing altered purpose enhancing lung viability, a research device was devised.MethodsThe (fig. 1) is...

I have read with great interest the article from Potger et al. (1), and commend the authors for the contribution they make in this investigation. While congratulating them on their work, I also raise the following points to continue what I believe is much needed discussion on the very important topic of gas-bubble transmission during extracorporeal circulation (ECC). To build an appropriate con...

We present a 62-year-old patient with COVID-19 pneumonia on Veno-venous (VV) Extracorporeal Membrane Oxygenation (ECMO) unique perturbations to pre and post oxygenator pressures due fibrin deposition in despite being Heparin/Bivalirudin infusion activated Partial Thromboplastin Time (aPTT) within therapeutic range of 60–80 seconds. On Day 8 ECMO support, it was noticed that flows steadily decre...

The development of the membrane oxygenator for pediatric cardiopulmonary bypass has been an incorporation of ideology and technological advancements with contributions by many investigators throughout the past two centuries. With the pursuit of this technological achievement, the ability to care for mankind in the areas of cardiac surgery has been made possible. Heart disease can affect anyone ...