Mothers and midwives who had participated in the Bristol randomized controlled trial of active versus physiologic management of the Third Stage of Labor were asked for their views. One hundred ninety-one mothers (11% of the total randomized) and 49 midwives completed self-administered questionnaires. Both mothers and midwives commented adversely about the length of the third stage under physiol...

Oxytocin, the main oxytocic-milk-ejecting-avian depressor principle of the posterior pituitary gland, the structure of which is shown in Fig. 1, possesses a number of chemical functional groups : a primary amino group in position 1, a phenolic hydroxyl group in position 2, three carboxamide groups in positions 4, 5, and 9, and a disulfide linkage in t.he 20.membered cyclic m0iet.y. The signific...

Sch'afer and Oliver3", the first to demonstrate the physiological activity of the pituitary gland, recorded observations of its effects upon the circulation in 1894, shortly after their discovery of the adrenal hormone. The first influence upon water metabolism to be discovered was diuresis (Magnus and Schafer, 190120). It was not until 191 0, however, that the pituitary gland was related to di...