Next-generation synthetic bone graft therapies will most likely be composed of resorbable polymers in combination with bioactive components. In this article, we continue our exploration of E1001(1k), a tyrosine-derived polycarbonate, as an orthopedic implant material. Specifically, we use E1001(1k), which is degradable, nontoxic, and osteoconductive, to fabricate porous bone regeneration scaffo...

R. S. DIAS, S. LÓPEZ*, R. M. PATIÑO, T. S. SILVA, J. C. SILVA FILHO, D. M. S. S. VITTI, M. R. S. R. PEÇANHA, E. KEBREAB AND J. FRANCE Centre for Nutrition Modelling, Department of Animal and Poultry Science, University of Guelph, Guelph, ON, N1 G 2W1, Canada 2 Instituto de Ganadería de Montaña, Universidad de León –Consejo Superior de Investigaciones Científicas, Departamento de Producción Anim...

Objective: The present study involved the preparation of Diclofenac sodium extended release hydrophobic matrix tablets formulated from Ethylcellulose polymer following its different grades, Ethocel Standard Premium and Ethocel Standard FP Premium. Methods: The matrix tablets were prepared with wet granulation method. Lubricated blends were characterized for physical properties like loose bulk d...

Heterogeneous nucleation of dicalcium phosphate dihydrate, CaHPO4•2H2O (DCPD) was studied on untreated planar fused silica and on three modified silica surfaces: octadecylsilyl (OTS) modified silica, human serum albumin treated OTS silica, and UV-oxidized 3-mercaptopropyltriethoxysilyl (MTS) modified silica. The supersaturation ratio of calcium and phosphate solution with respect to DCPD was ke...

Brushite (dicalcium phosphate dihydrate) and monetite (dicalcium phosphate anhydrous) are of considerable interest in bone augmentation owing to their metastable nature in physiological fluids. The anhydrous form of brushite, namely monetite, has a finer microstructure with higher surface area, strength and bioresorbability, which does not transform to the poorly resorbable hydroxyapatite, thus...

Calcium phosphate cement (CPC) sets in situ to form resorbable hydroxyapatite with chemical and crystallographic similarity to the apatite in human bones, hence it is highly promising for clinical applications. The objective of the present study was to develop a CPC that is fast setting and has high strength in the early stages of implantation. Two approaches were combined to impart high early ...

PURPOSE To compare the long-term caries increment associated with the use of two dentifrices: (1) a test dentifrice containing 0.836% sodium monofluorophosphate (1100 ppm F) in a dicalcium phosphate dihydrate base plus 10% xylitol; and (2) a positive control dentifrice containing 0.836% sodium monofluorophosphate (1100 ppm F) in a dicalcium phosphate dihydrate base. MATERIALS AND METHODS Thre...

The basal activity of Ca2+-ATPase in two isolates (NL56, UNC) and two clones (D6, W2) of P.falciparum was assessed. The effects of various concentrations of chloroquine phosphate and toxic concentrations of lead acetate were also evaluated in the clones and strains of P.falciparum. The Ca2+-ATPase activity was measured by monitoring the rate of release of inorganic phosphate from the gamma-posi...

An experiment was conducted to evaluate the effects of phytase supplementation on the growth performance, nutrients utilization and bone mineralization in broiler chickens. Day-old broiler chicks (n=480) were equally devided into eight treatment groups and fed maize or wheat based isocaloric, isonitrogenous and isocalcium diets having two non phytate phosphorus (NPP) concentrations (0.50% and 0...