PURPOSE To investigate whether the pattern reversal visual evoked potential can be useful in the diagnosis and management of macular hole patients. METHODS The pattern reversal visual evoked potential was measured in 66 patients with a macular hole and in 43 healthy control subjects. Check sizes of 34', 17' and 10' were applied. RESULTS Results showed that, for the check sizes of 34', 17' a...

Background: Multiple sclerosis (MS) is characterized by a great heterogeneity of both its clinical course and the aspect of the lesions. The main purpose of this study is to evaluate the neuromuscular disorders in MS using electrophysiological parameters, in order to enable the rehabilitation physician to set the goals of a prophylactic intervention. The major research question addressed here i...

Introduction: Emotional stimulus is processed automatically in a bottom-up way or can be processed voluntarily in a top-down way. Imaging studies have indicated that bottom-up and top-down processing are mediated through different neural systems. However, temporal differentiation of top-down versus bottom-up processing of facial emotional expressions has remained to be clarified. The present st...

The objective was to study the P100 latency and amplitude in Visual Evoked Potentials (VEPs) with dominant and non-dominant eye individuals. VEPs were recorded in 30 dominant and non-dominant eye males using a Neuropack machine. Latency and Amplitude of VEPs (P100) were measured and analyzed statistically. The effect of eye dominance as seen in was that the latency of P100 was less in the domin...

Gene expression profiling in E 11 mouse embryos identified high expression of the long noncoding RNA (lncRNA), LNCRNA-HIT in the undifferentiated limb mesenchyme, gut, and developing genital tubercle. In the limb mesenchyme, LncRNA-HIT was found to be retained in the nucleus, forming a complex with p100 and CBP. Analysis of the genome-wide distribution of LncRNA-HIT-p100/CBP complexes by ChIRP-...

A case of a 14-year-old girl suffering from intense headaches is presented. At the first pediatrician's examination, patient had regular findings. Prolonged P100 wave latencies were found by testing visual evoked potentials. After further examination following repeated headaches, Arnold Chiari type I malformation was diagnosed. classified as downward displacement one or both cerebellar tonsils ...

We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor. The nuclear factor kappa-light-chain-enhancer of activated B cells 2 (NFκB2)/p100 was overexpressed after galactomannan challenge. Knocking down NFκ...

Properties of a percentile-based rating scale needed in bibliometrics are formulated. Based on these properties, P100 was recently introduced as a new citation-rank approach (Bornmann, Leydesdorff,&Wang, in press). In this paper, we conceptualize P100 and propose an improvement which we call P100_. Advantages and disadvantages of citation-rank indicators are noted.

BACKGROUND Constitutive activation of the alternative NF-κB pathway leads to marginal zone B cell expansion and disorganized spleen microarchitecture. Furthermore, uncontrolled alternative NF-κB signaling may result in the development and progression of cancer. Here, we focused on the question how does the constitutive alternative NF-κB signaling exert its effects in these malignant processes. ...

Vascular endothelial growth factor (VEGF) is an endothelium-specific mitogen that induces angiogenesis and increases vascular permeability. These processes involve regulation of cell-cell adhesion, but molecular mechanisms have yet to be fully established. p120, also termed p120(ctn), and its variant p100 are catenins which associate with cadherins and localize to adherens junctions. VEGF was r...