objective: to compare the effect of intrathecal midazolam versus neostigmine added to lidocaine on the duration of sensory block and the duration of postoperative pain relief in women undergoing colporaphy in spinal anesthesia. materials and methods: in this double blind clinical trial we evaluated 60women (asa) i,ii that were candidate to elective colporaphy. the patients were randomly divided...

normal 0 false false false en-us x-none ar-sa background: the aim of this study was to compare the postoperative pain scores and morphine requirements between spinal anesthesia (sa) with hyperbaric bupivacaine 0.5% and general anesthesia (ga) with 1 minimal alveolar concentration (mac )of isoflurane in 50% n2o and o2 after elective lower abdominal surgery. materials and methods: in this randomi...

Over 234,000 rats were used in regulated procedures in the UK in 2014, many of which may have resulted in some degree of pain. When using animals in research, there is an ethical and legal responsibility to alleviate or at least reduce pain to an absolute minimum. To do this, we must be able to effectively assess pain in an accurate and timely manner. The Rat Grimace Scale (RGS) is a pain asses...

Background Certain behaviors can be adopted by women to cope with labor pain according to their individual characteristics, which are currently called behavioral indicators during labor pain, and include facial expressions, verbal expressions, tone of voice, body movements, degree of relaxation, and respiratory system functioning during delivery. Moreover, severity of pain and duration of labor...

OBJECTIVES To review the duration of pain relief after initial and repeated radiofrequency neurotomy (RFN) for cervical and lumbar zygapophysial joint pain. METHODS We searched PubMed to identify all articles that met review criteria for in-depth analysis, synthesis, and review. RESULTS Data from 16 articles are reported in this review, including 8 cervical studies, 7 lumbar studies, and 1 ...

OBJECTIVE Neuropathic pain causes patients feel indescribable pain. Deep Brain Stimulation (DBS) is one of the treatment methods in neuropathic pain but the action mechanism is still unclear. To study the effect and mechanism of analgesic effects from DBS in neuropathic pain and to enhance the analgesic effect of DBS, we stimulated the ventral posterolateral nucleus (VPL) in rats. METHODS To ...

Analgesic efficacy varies depending on the pain syndrome being treated. One reason for this may be a differential effect of individual pain syndromes on the function of the endogenous pain control circuits at which these drugs act to produce analgesia. To test this hypothesis, we examined the effects of diverse (i.e., ongoing inflammatory, neuropathic, or chronic widespread) pain syndromes on a...