Policy [TOP] Magnetic resonance ‒ guided high-intensity ultrasound ablation may be considered medically necessary for pain palliation in adult patients with metastatic bone cancer who failed or are not candidates for radiotherapy. Magnetic resonance-guided high-intensity ultrasound ablation is considered investigational in all other situations including but not limited to:  Treatment of uterin...

Policy [TOP] Magnetic resonance ‒ guided high-intensity ultrasound ablation may be considered medically necessary for pain palliation in adult patients with metastatic bone cancer who failed or are not candidates for radiotherapy. Magnetic resonance-guided high-intensity ultrasound ablation is considered investigational in all other situations including but not limited to:  Treatment of uterin...

Opioids have been the mainstay for pain relief and palliation over a long period of time. They are commonly abused by drug addicts and such dependence usually imparts severe physiologic effects on multiple organ systems. The negative impact of opioids on the endocrine system is poorly understood and often underestimated. We describe a patient who developed severe suppression of the hypothalamic...

UNLABELLED This retrospective study compared the effects of single and multiple administrations of (186)Re-hydroxyethylidenediphosphonate ((186)Re-HEDP) on palliation and survival of prostate cancer patients presenting with more than 5 skeletal metastases. METHODS A total of 60 patients were divided into 3 groups. Group A (n = 19) consisted of patients who had received a single injection; gro...

background: in conventional radiation therapy, regarding normal tissue tolerance, the treatment of bulk tumors is one of the remaining challenges. grid radiation therapy (grt) is a technique to deliver high doses, approximately 15 – 20 gy per fraction, to several small volumes located in a large radiation field. this can be performed using a grid block. the current work has concentrated on the ...

Background: Bone is the most common site for metastases in cancer and may complicate a wide range of malignancies. Radiotherapy successful efficient method pain palliation it can prevent morbidity bone metastases. Pain flare event, occurring almost 40% patients that receive palliative radiotherapy. Dexamethasone has shown possibility prevention such flare. Objective: This study aimed to investi...

Painful osseous metastases are the major cause of cancer-related pain in metastasized prostate cancer. In hormone refractory prostate cancer multiple painful metastases can be treated with radionuclides. Initially, Strontium-89 was successfully used for pain palliation with pain relief in more than half the patients. More recently, radionuclides with shorter physical half-lives such as Rhenium ...

Neuropathic pain is a large-scale epidemiological problem affecting 13-26% of the diabetic population. The complex aetiology and pathophysiology coupled with the lack of a diagnostic test for the underlying cause renders the assessment of neuropathic pain subjective and the treatment difficult, especially as current licensed treatments are limited in their application towards the attainment of ...

Various single or multi-modality therapeutic options are available to treat pain of bone metastasis in patients with prostate cancer. Different radionuclides that emit β-rays such as (153)Samarium and (89)Strontium and achieve palliation are commercially available. In contrast to β-emitters, (223)Radium as a α-emitter has a short path-length. The advantage of the α-emitter is thus a highly loca...