Partially self-complementary dodecadeoxyribonucleotides containing a fluorescent nucleoside, 3-beta-D-2'-deoxyribofuranosyl-2, 7-dioxopyrido[2, 3-d]pyrimidine (pyridopyrimidine deoxynucleoside, dF) were synthesized by the phosphotriester solidphase method. A dodecanucleotide d(GGGAAFGTTCCC) pairing the analog and guanine at the centre of the chain showed a higher melting temperature than the co...

‎in this paper‎, ‎we present a novel approach for image selective smoothing by the evolution of two paired nonlinear‎ ‎partial differential equations‎. ‎the distribution coefficient in de-noising equation controls the speed of distribution‎, ‎and is‎ ‎determined by the edge-strength function‎. ‎in the previous works‎, ‎the edge-strength function depends on isotropic‎ ‎smoothing of the image‎...

OBJECTIVE To provide a practical guidance for the analysis of N-of-1 trials by comparing four commonly used models. METHODS The four models, paired t-test, mixed effects model of difference, mixed effects model and meta-analysis of summary data were compared using a simulation study. The assumed 3-cycles and 4-cycles N-of-1 trials were set with sample sizes of 1, 3, 5, 10, 20 and 30 respectiv...

The presence of tumor-infiltrating lymphocytes (TILs) is associated with favorable long-term outcome in breast cancer. However, little is known about changes in TILs during metastatic progression. To confirm our hypothesis that malignant tumors escape from the host immune system during metastasis, we evaluated the percentage of TILs in paired samples of primary and metastatic breast tumors. We ...

The purpose of this study was to determine the effect variations in leg muscle training on jumping results extracurricular volleyball players at SMPN 1 Bangkalan. Which aims find out whether there is an research method uses a quasi-experimental design (pseudo-experiment). data analysis technique used paired sample t-test, with t-test where t-count = 16.20 significant level obtained that value t...

To determine the extent to which the visual experience of one eye may influence the refractive development of its fellow eye, we analyzed the data of untreated (UT) eyes of monkeys that received different types of unilateral pattern deprivation. Subjects were 15 juvenile rhesus monkeys, with five monkeys in each of three treatment groups: aphakic eyes with optical correction (AC), aphakic eyes ...