OBJECTIVE To evaluate the safety and efficacy of high intensity focused ultrasound for palliation of inoperable pancreatic cancer in humans. PATIENTS Eighty-nine patients with advanced pancreatic cancer were treated with high intensity focused ultrasound. There were 4 patients with stage II, 39 patients with stage III, and 46 patients with stage IV disease. The location of the tumors was as f...

recently reported the clinical response to chemotherapy in patients with advanced pancreatic cancer. To assess the clinical efficacy of the treatment, they used pain assessment by the patients themselves (employing a pain assessment card) and the amount of morphine consumed. This type of assessment is already used in the USA and will be widely applied in Japan in the future. However, there are ...

In the past four decades, the incidence of pancreatic cancer has increased steadily in most of the world and now this type of tumor ranks as the fifth or sixth most frequent cause of death due to cancer in many western countries [1]. For example, in 2000, worldwide figures for pancreatic cancer were projected at 216,400 new cases and 213,500 deaths [2]; the data coming from the United States in...

Pancreatic cancer is one of the leading causes death worldwide, majority patients are initially diagnosed at an advanced stage and pain most common symptom. The best management represents a real challenge to ensure better quality life for patients. aim this study evaluate therapeutic in daily clinical practice our medical oncology department. We carried out retrospective on treated pancreatic M...

High-intensity focused ultrasound (HIFU) is a novel therapeutic modality that permits noninvasive treatment of various benign and malignant solid tumors, including prostatic cancer, uterine fibroids, hepatic tumors, renal tumors, breast cancers, and pancreatic cancers. Several preclinical and clinical studies have investigated the safety and efficacy of HIFU for treating solid tumors, including...

Pain is the main symptom of pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC). in may be visceral, somatic or neuropathic origin. produced by tissue damage, inflammation, obstruction and infiltration. Visceral nociceptive signals caused damage to upper abdominal viscera are carried along sympathetic fibers, which travel celiac plexus nerves ganglia, found at T12-L2 vertebral levels, an...

background: pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ercp) and may cause significant morbidity and even death. there is no effective prophylactic intervention for patients with average risk yet. this study aims to investigate preventive effect of aggressive hydration for post-ercp pancreatitis. materials and methods: in a double-blind controlled ...