• Objective: To review the diagnosis and management of pancreatic cystic lesions. • Methods: Narrative review of the literature. • Results: Pancreatic cystic lesions are clinically relevant as some are precursor lesions to pancreatic adenocarcinoma. Mucinous cystic neoplasms and intraductal papillary mucinous neoplasms are 2 commonly encountered pre-cancerous pancreatic cysts. Many cysts are id...

BACKGROUND Accurate tests to diagnose adenocarcinoma and high-grade dysplasia among mucinous pancreatic cysts are clinically needed. This study evaluated the diagnostic utility of amphiregulin (AREG) as a pancreatic cyst fluid biomarker to differentiate non-mucinous, benign mucinous, and malignant mucinous cysts. METHODS A single-center retrospective study to evaluate AREG levels in pancreati...

A 56-year-old woman with a symptomatic pancreatic pseudocyst refractory to conservative treatment was referred to us for endoscopic ultrasound-guided pancreatic pseudocyst drainage (EUSPPD). EUS showed a 12-cm cyst near the pancreatic body and tail. The cyst was punctured using a 19-gauge fine needle aspiration (FNA) needle from the stomach under EUS imaging, after careful examination of the in...

An increased number of pancreatic cysts are being diagnosed due to the increased usage of cross-sectional imaging. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) cytology and molecular analysis of these cystic lesions have led to their better detection and characterization. The aim of this review is to assess the value of cyst fluid analysis for the differential diagnosis of pa...

A lymphoepithelial cyst (LEC) is a rare pancreatic lesion, histologically showing squamous epithelia, dense lymphoid tissues, and a keratin substance. Cross-section images of the pancreatic LEC typically show a well demarcated unilocular or multilocular cyst without a solid component. Here we report a rare case of pancreatic LEC in which multiple floating ball-like components were depicted via ...

Pancreatic true cysts represent a rare, heterogeneous group of pancreatic tumors; therapeutic strategy is based on patient's general status, cyst topography, and especially the estimated risk of malignancy. This paper aim is to present 7 cases of pancreatic true cysts, operated on a six years period (January 2004-January 2010) in our surgical clinic: 2 men and 5 women, aged between 24-61 years ...

Pancreatic cysts represent a small proportion of pancreatic diseases, but their incidence has been recently increasing. Most pancreatic cysts are identified incidentally, causing a dilemma for both clinicians and patients. In contrast to ductal adenocarcinoma, neoplastic pancreatic cysts may be cured by resection. In general, pancreatic cysts are classified as neoplastic or non-neoplastic cysts...

BACKGROUND/AIMS The aim of this study was to compare the surgical drainage of large, symptomatic pancreatic cysts (>5 cm) with single- and multi-channel endoscopic drainage. MATERIALS AND METHODS In the period 2005-2010, we treated 112 patients with post-inflammatory pancreatic cysts. Thirty-six patients underwent surgical internal drainage. The remaining group of patients was treated endosco...

BACKGROUND AND OBJECTIVES: Pseudo pancreatic cyst is a common complication of pancreatitis. Accurate diagnosis and timely management is important. This study is to know the various etiological factors, relative frequency of occurrence of pseudo pancreatic cyst in relation to age and sex, establish accurate diagnosis by various investigations and to study various modes of management like conserv...

CONTEXT Molecular analysis of pancreatic cyst fluid obtained by EUS-FNA may increase diagnostic accuracy. We evaluated the utility of cyst-fluid molecular analysis, including mutational analysis of K-ras, loss of heterozygosity (LOH) at tumor suppressor loci, and DNA content in the diagnoses and surveillance of pancreatic cysts. METHODS We retrospectively reviewed the Columbia University Panc...