Amaç: Şizofrenide bilişsel bozulmalar şizofreninin değişik belirti alt tipleriyle bağlantılıdır. Paranoid tip şizofrenide bilişsel işlevlerin daha iyi korunduğu öne sürülmüştür. Bu çalışmada, nöropsikolojik ölçümlerin, paranoid şizofreni hastalarını paranoid olmayanlardan ayrıştırıp ayrıştırmadığının değerlendirilmesi amaçlanmıştır. Yöntemler: Bu çalışmaya DSM-IV ölçütlerine göre 26 paranoid ti...

BACKGROUND The ability to inhibit inappropriate or unwanted actions is a key element of executive control. The existence of executive function deficits in schizophrenia is consistent with frontal lobe theories of the disorder. Relatively few studies have examined response inhibition in schizophrenia, and none in adolescent patients with early-onset schizophrenia (EOS). METHODS Twenty-one adol...

BACKGROUND Insecure attachment styles have received theoretical attention and some initial empirical support as mediators between childhood adverse experiences and psychotic phenomena; however, further specificity needs investigating. The present interview study aimed to examine (i) whether two forms of poor childhood care, namely parental antipathy and role reversal, were associated with subcl...

INTRODUCTION One of the main aims of research on schizophrenia has been to pinpoint the early symptoms and signals of the disease before its appearance. OBJECTIVES We have examined the diagnoses previously given to patients before they were diagnosed of schizophrenia. METHOD This is a case-control study in which we used a data register including the fields of minimum basic data set (MBDS) w...

BACKGROUND There has been renewed interest in the influence of affect on psychosis. Psychological research on persecutory delusions ascribes a prominent role to cognitive processes related to negative affect: anxiety leads to the anticipation of threat within paranoia; depressive negative ideas about the self create a sense of vulnerability in which paranoid thoughts flourish; and self-consciou...

Introduction: Schizophrenia is a chronic mental illness, whose aetiology is still unclear; therefore, information about differences in serum protein patterns may improve the understanding of the pathophysiology of schizophrenia. The goal of this study was to use the proteomic approach to identify altered protein levels in the serum samples from patients with schizophrenia. Methods: Blood wa...

Attentional skills among people with schizophrenia may be related to deficits in affect perception. Such deficits can dramatically inhibit appropriate social functioning. We examined attention and affect perception in a sample of 65 people diagnosed with chronic schizophrenia. We used Mirsky's four factor model of attention to assess attentional functioning. To measure affect perception, we use...

OBJECTIVE Theory of Mind (ToM) is considered an essential element of social cognition. In younger schizophrenia patients, ToM impairments have extensively been demonstrated. It is not clear whether similar impairments can be found in older schizophrenia patients and if these impairments differ between older patients with early-onset and late-onset schizophrenia. METHODS Theory of Mind abiliti...