Sequestration of Plasmodium falciparum-infected erythrocytes (Pf-IRBC) in postcapillary brain endothelium is a hallmark of cerebral malaria (CM) pathogenesis. There is a correlation between adherent Pf-IRBC and increased expression of intercellular cell adhesion molecule 1 (ICAM-1), which is also a receptor for Pf-IRBC on human brain microvascular endothelial cells (HBMEC). The underlying mecha...

Twenty-five strains of enterotoxigenic (tox(+)) Escherichia coli isolated in India, Bangladesh, and the U.S.A. were shown to produce vascular permeability factor (PF) activity as well as diarrheagenic activity. Sixteen strains of non-enterotoxigenic E. coli were found to be PF negative. The PF response elicited by tox(+)E. coli isolated in the U.S.A. from cases of infantile diarrhea was qualita...

Four in vitro experiments (Exp.) were conducted to evaluate lavender essential oil (LEO) effects at 0 (control), 250 (low dose), 500 (medium dose), 750 and 1000 µL per L(high doses) of incubation medium on rumen gas production kinetics (Exp.1), ruminal digestibility and fermentation (Exp.2), methane production (Exp.3) and rumen acidosis (Exp.4). The asymptote of gas production (A) incr...

Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is a newly identified virus with tumorigenic potential. Here, we cloned and expressed the DNA polymerase (Pol-8) of KSHV and its processivity factor (PF-8). Pol-8 bound specifically to PF-8 in vitro. Moreover, the DNA synthesis activity of Pol-8 was shown in vitro to be strongly dependent on PF-8. Addition of PF-8 to Pol-8 ...

Subsurface migration of greenhouse gases and other gaseous phase contaminants is predominantly controlled by soil gas diffusion coefficient (Dp) and its variations with soil-air content (ε) and soil moisture (or potential) status. Buckingham (1904) stated that Dp is proportional to ε X with X characterizing the tortuosity and connectivity of air-filled pore space. In the Buckingham model, as we...

Background: The price of conventional protein sources like soybean and peanut has increased markedly in recent years resulting urgent need for exploring alternate sources. Due to increase availability cottonseed meal (CSM) cotton-growing areas India as compared other oil seed meals, CSM is becoming one the major components concentrate mixture (CM) fed animals. Methods: A study was undertaken as...

the present investigation entails a procedure by which the surface tension and viscosity of liquids could be redicted.to this end, capillary experiments were performed for porous media by utilizing fifteen different liquids and powders. the time of capillary rise to a certain known height of each liquid in a particular powder was recorded. two artificial neural networks (anns) were designed and...

Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma-associated herpesvirus (KSHV) ORF59 protein (PF-8) is a processivity factor for HHV-8 DNA polymerase (Pol-8) and is homologous to processivity factors expressed by other herpesviruses, such as herpes simplex virus type 1 UL42 and Epstein-Barr virus BMRF1. The interaction of UL42 and BMRF1 with their corresponding DNA polymerases is essential for v...

In this two-part paper, we consider the multiantenna multihop relay channels in which the source signal arrives at the destination through N independent relaying hops in series. The main concern of this work is to design relaying strategies that utilize efficiently the relays in such a way that the diversity is maximized. In part I, we focus on the amplify-and-forward (AF) strategy with which t...

The c-Met pathway has been implicated in a variety of human cancers for its critical role in tumor growth, invasion, andmetastasis. PF-04217903 is a novelATP-competitive small-molecule inhibitor of c-Met kinase. PF04217903 showed more than 1,000-fold selectivity for c-Met compared with more than 150 kinases, making it one of the most selective c-Met inhibitors described to date. PF-04217903 inh...