The genome of the protozoan parasite Plasmodium falciparum, the causative agent of the most lethal type of human malaria, contains a single gene annotated as encoding a carbonic anhydrase (CAs, EC 4.2.1.1) thought to belong to the α-class, PfCA. Here we demonstrate the kinetic properties of PfCA for the CO2 hydration reaction, as well as an inhibition study of this enzyme with inorganic and com...

BACKGROUND We would like to analyze the risk factors of no thumb test among knee alignment tests during total knee arthroplasty surgery. METHODS The 156 cases of total knee arthroplasty by an operator from October 2009 to April 2010 were analyzed according to preoperative indicators including body weight, height, degree of varus deformity, and patella subluxation and surgical indicators such ...

BACKGROUND Femoral sulcus angle is particularly important in clinical evaluation of patellofemoral joint. Individuals show considerable differences in asymmetrical dimensions of the femur. OBJECTIVES To determine the size of femoral sulcus angles in adult black Malawians using the skeletal collection in the department of Anatomy, College of Medicine and assess their gender differences; to com...

Treatment of ventricular arrhythmias with radiofrequency (RF) catheter ablation can be limited by insufficient lesion size and depth, especially within diseased myocardium. A recent investigation using a force-sensing RF (30 watts / 30 seconds) described average depths 5.1 mm healthy tissue 2.0 scar. To compare measurements ultra-low temperature cryoablation (ULTC) versus pulsed field (ULTC com...

A three-dimensional dynamic model of the tibiofemoral and patellofemoral articulations was developed to predict the motions of knee implants during a step-up activity. Patterns of muscle activity, initial joint angles and velocities, and kinematics of the hip and tinkle were measured experimentally and used as inputs to the simulation. Prosthetic knee kinematics were determined by integration o...

One of the main problems after total knee arthroplasty is pain in the patellofemoral joint, which in some cases leads to revision surgery. Rotation of the femoral component has a significant influence on the path followed by the patella within the patellofemoral joint. We examined the influence of rotation of the femoral component after total knee arthroplasty on patellar tilt. We retrospective...

<abstract><p>Among the triangle congruence axioms, side-side-angle (SsA) axiom states that two triangles are congruent if and only pairs of corresponding sides angles opposite longer equal. We construct sequences in which items satisfy a modified condition. require shorter be The locus intersection points other is derived to hyperbola, generalized form defined by complete quadrilate...

BACKGROUND The single-leg squat on a 25 degrees decline board has been described as a clinical assessment tool and as a rehabilitation exercise for patients with patellar tendinopathy. Several assumptions have been made about its working mechanism on patellar load and patellofemoral forces, but these are not substantiated by biomechanical evaluations. AIM To investigate knee moment and patell...

[Purpose] To compare the effects of open-chain exercise (OCE) and closed-chain exercise (CCE) for patients after medial patellofemoral ligament (MPFL) reconstruction. [Subjects and Methods] Forty patients after MPFL reconstruction were randomly divided into an OCE group and a CCE group. All the patients were evaluated at four different time points. [Results] The mean change of thigh circumferen...

OBJECTIVE To investigate the relationship between the q-angle and anterior knee pain severity, functional capacity, dynamic knee valgus and hip abductor torque in women with patellofemoral pain syndrome (PFPS). METHODS This study included 22 women with PFPS. The q-angle was assessed using goniometry: the participants were positioned in dorsal decubitus with the knee and hip extended, and the ...