OBJECTIVES The study assessed dexmedetomidine utilization and practice variation over time in ventilated pediatric intensive care unit (PICU) patients; and evaluated differences in hospital outcomes between high- and low-dexmedetomidine utilization hospitals. STUDY DESIGN This serial cross-sectional analysis used administrative data from PICU admissions in the pediatric health information sys...

The second half of the 20th century has produced an explosion of knowledge applied to the critically ill. The pathophysiology of life-threatening processes such as shock, respiratory failure, and increased intracranial pressure has been explored extensively. Advances in electronic patient monitoring, pharmacology, and improvement in transport systems are but a few of the factors that have drast...

OBJECTIVE To carry out surveillance of central line associated bloodstream infections in a Pediatric intensive care unit (PICU) and determine associated risk factors. METHODS This prospective study was conducted over 1.5 years in the PICU. CDC definitions for these infections were followed and associated risk factors were identified. RESULTS Of 265 enrolled children with central line, 13 de...

Epidemiology During the past decade, the reported incidence of brain death in older infants and children has ranged from 0.65% to 1.2% of patients admitted to the pediatric intensive care unit (PICU). In one study, the percentage of brain death among deaths overall was 31.4% in children older than 1 month and 6.3% in neonates. Data from Loma Linda University Children’s Hospital revealed that 28...

OBJECTIVE To study posttraumatic stress disorder (PTSD) in parents after unexpected pediatric intensive care unit (PICU) treatment of their child and to identify risk factors for its development. METHOD Parents completed PTSD questionnaires 3 and 9 months (N = 190) after PICU treatment. Risk factors included pretrauma data, medical data, social demographics and posttraumatic stress responses ...

Children frequently experience more painful, stressful, and traumatic medical procedures treatments in the pediatric intensive care unit (PICU) than when they are hospitalized general wards. An essential part of PICU is providing critically ill children with appropriate sedation analgesia. Finding perfect combination adequate analgesia sufficient a patient group wide range ages, sizes, developm...

INTRODUCTION The aim was to investigate the prevalence of endotoxemia in children admitted to pediatric intensive care unit (PICU), and its association with disease severity and outcome. METHODS We conducted a prospective, observational cohort study of children admitted to PICU at St. Mary's Hospital, London over a 6-month period. One hundred consecutive patients were recruited. Demographic a...

objective critical illness polyneuropathy and myopathy (cipnm) is a major complication of severe critical illness. previous studies have suggested that many risk factors such as sepsis, multiorgan failure, and neuromuscular blocking agents play a role in cipnm pathogenesis. the aim of this study was to evaluate possible risk factors in the development of cipnm in a pediatric intensive care unit...