The optimal use of kidneys from small pediatric deceased donors remains undetermined. Using data from the Scientific Registry of Transplant Recipients, 2886 small (< 21 kg) pediatric donors between 1993 and 2002 were identified. Donor factors predictive of kidney recovery and transplantation (1343 en bloc; 1600 single) were identified by logistic regression. Multivariable Cox regression was use...

OBJECTIVES This study sought to evaluate graft outcome of kidneys from deceased-donor pediatric donors in adult recipients, and compare it with outcomes of kidney transplants from adult donors. MATERIALS AND METHODS This historical cohort study involved 2 groups. Group 1 included 23 first kidney adult recipients who received their first renal transplant from pediatric deceased-donor donors. G...

background: cytomegalovirus (cmv) disease is an important cause of death and possibly transplant rejection in kidney transplant (kt) patients. this study was conducted to investigate the incidence and risk factors of cmv disease in kidney transplant patients. methods: all end-stage renal disease (esrd) patients who underwent kidney transplantation during 1998-2014 and their donors were assessed...

BK polyomavirus (BKV) is an emerging pathogen in immunocompromised individuals. BKV subtype III is rarely identified and has not previously been associated with disease. Here we provide the whole-genome sequence of a subtype III BKV from a pediatric kidney transplant patient with polyomavirus-associated nephropathy.

Kidney transplant is the treatment of choice for children and adolescents with end-stage renal disease because transplantation improves quality of life and survival to a far greater extent than chronic dialysis. Unfortunately, however, transplantation does not completely normalize the excess risks associated with end-stage renal disease nor do transplanted allografts function indefinitely. In t...

BACKGROUND Clinicians may be reluctant to transplant small pediatric kidneys that have prolonged cold ischemia time (CIT) for fear of an additional deleterious effect because pediatric grafts are thought to be more sensitive to ischemia. We aimed to assess the risks associated with transplantation of small pediatric kidneys with prolonged CIT. METHODS We performed a retrospective cohort study...

OBJECTIVES To evaluate the efficacy and safety of losartan and enalapril in pediatric kidney transplant recipients. MATERIALS AND METHODS A retrospective review was performed in 31 pediatric kidney transplant recipients who were treated with losartan (50 mg/d, oral) for 1 to 6 months because of mild hypertension and persistent proteinuria. All patients were treated concurrently with enalapril...