Abstract   Objective: To evaluate and review our experience with pediatric spinal injuries and   factors affecting outcome, the authors conducted a retrospective clinical study of 43   cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (January   1999 to December 2003).   Methods: Forty-three children with spinal injuries were studied retrospectively   over four y...

introduction: the aim of this study was to report surgical strategies and clinical outcomes for thoraco-lumbar intradural lipomas. intraspinal lipomas are rare congenital histologically benign neoplasms, which account for less than 1% of all spinal cord tumors. these tumors are most frequently found in the lumbosacral area as components of a dysraphic state, however, intramedullary lipomas are ...

multiple primary tumors in a single patient are relatively rare when four or more distinct lesions are considered. herein, we report a case of woman with four different primary tumors: meningioma, renal angiomyolipoma, spinal ependymoma and high-grade soft tissue sarcoma. there was no family history and hereditary syndrome. the genetic analysis was completely normal. to best of our knowledge, t...

Pediatric brain tumors are the most common solid tumors in children and are also a leading culprit of cancer-related fatalities in children. Pediatric brain tumors remain hard to treat. In this study, we demonstrated that medulloblastoma, pediatric glioblastoma, and atypical teratoid rhabdoid tumors express significant levels of acid ceramidase, where levels are highest in the radioresistant tu...

PURPOSE Adult cancer is frequently preceded by a period of prolonged chronic inflammation caused by infectious microbial agents or physical or chemical irritants. By contrast, an association between the classic pediatric neoplasias and inflammatory triggers is only rarely recognized. We hypothesized that the difference could be reflected in the inflammatory cell infiltrates of pediatric and adu...

Pediatric liver tumors account for approximately 1% of all liver tumors and up to 2% of all pediatric malignancies [1,2]. While the overall incidence of liver tumors is rare, the liver remains the third most common organ of origin for solid abdominal tumors in the pediatric population [3]. The majority of pediatric liver tumors, both benign and malignant, occur (almost) exclusively in children....