background: acute myeloid leukemia (aml) is a malignant disorder involving blood cells, characterized by obstructed or distorted differentiation of hematopoietic stem cells. in cytogenetically normal aml (cn aml), molecular abnormalities in npm, flt3, cebpa, and baalc genes are observed. initially, high baalc (brain and acute leukemia cytoplasmic gene) expression was introduced in a study on am...

abstract background immune thrombocytopenic purpura (itp) is the most prevalent cause of thrombocytopenia in children. despite the importance of itp in children under 2- years old, only a few publications are available in the literature. itp usually presents itself as   isolated thrombocytopenia and mucocutaneous bleeding. materials and methods this study was conducted on 187 under 2- year-old ...

background: clinical reasoning process leads clinician to get purposeful steps from signs and symptoms toward diagnosis and treatment. this research intends to investigate the effect of teaching clinical reasoning on problem-solving skills of medical students.   methods: this research is a semi-experimental study. nineteen medical student of the pediatric ward as case group participated in a tw...

background brain abscess is an infrequent complication of meningitis, including cases caused by gram-negative enteric bacteria and klebsiella in neonates. brain abscess in neonates associated with high morbidity and mortality.recently, incidence of the disease is increasing because of increased predisposing factors. patients and method three cases of brain abscess in neonates are reported, 2 of...

objectives: midazolam with variable dosages has been used to induce sedation in pediatric dentistry. the aim of this study was to compare the efficacy of two dosages of oral midazolam for conscious sedation of children undergoing dental treatment. materials and methods: in this randomized crossover double blind clinical trial, 20 healthy children (asa i) aged three to six years with negative or...

trauma is the most common cause of mortality and morbidity in pediatric population. caring for the injured child requires special knowledge, precise management, and scrupulous attention to details. all clinicians who are responsible for the care of a pediatric trauma patient, including pediatricians, pediatric emergency room clinicians, and trauma surgeons, must be familiar with every tenet of ...

childhood hepatitis b virus (hbv) infection causes both medical and public health challenges. infants who acquire hbv parentally have up to 90% risk of developing chronic hbv infection. it is now estimated that approximately 10% of worldwide cancers are attributable to viral infection, with the vast majority (>85 %) occurring in the developing world. in this distribution, elevated rate and prev...

introduction: pain may be described as a sensation of hurt or strong discomfort and is the body's way of sending message to the brain that an injury has occurred. pain medicines block these messages or reduce their effect on the brain. accurate administration of analgesia have a long –lasting effect on children whole experience of medical care and affects parents' and children's ...

minimal change disease (mcd) is the leading cause of childhood nephrotic syndrome (ns). therefore in pediatrics nephrotic syndrome, most children beyond the first year of life will be treated with corticosteroids without an initial biopsy. children with ns often display a number of calcium homeostasis disturbances causing abnormal bone histology, including hypocalcemia, reduced serum vitamin d ...

background: the graduated dentists who are working for the community health services are considered to be better judges to comment on the educational needs in accordance with the society prerequisites. the aim of this study was to investigate the educational provisions of the department of pediatric dentistry from the viewpoints of the graduated dentists of shiraz dental school. methods: a tota...