BACKGROUND Unfractionated heparin has been the primary anticoagulant therapy for percutaneous coronary intervention for >20 years. Despite the availability of rapid "point of care" testing, little clinical data defining the optimal level of anticoagulation are available. Furthermore, recent reports have advocated the use of low-dose heparin regimens in the absence of large-scale, well-conducted...

BACKGROUND Little is known about the impact of technological and pharmacological advances on long-term outcome after percutaneous coronary intervention in general clinical practice. METHODS AND RESULTS We analyzed in-hospital and long-term outcome of 24,410 percutaneous coronary interventions among 18,575 unique patients who underwent percutaneous coronary intervention at Mayo Clinic over 25 ...

INTRODUCTION A number of studies reported on a possible increased risk of morbidity and mortality after coronary artery bypass grafting in patients with prior percutaneous coronary intervention. METHODS A systematic review and meta-analysis of studies comparing the outcome of patients undergoing coronary surgery with or without prior percutaneous coronary intervention was performed. Only stud...

BACKGROUND The coexistence of peripheral artery disease (PAD) and multilevel atherosclerosis increases death and stroke rates in patients with coronary artery disease (CAD). Due to many comorbidities these patients are often treated conservatively without revascularisation. AIM To investigate whether complex percutaneous cardiovascular interventions for CAD and PAD may improve prognosis and l...

background: the aim of the present study was to develop a scoring system for predicting 1-year major adverse cardiac events (mace), including mortality, target vessel or target lesion revascularization, coronary artery bypass graft surgery, and non-fatal myocardial infarction after percutaneous coronary intervention (pci). methods: the data were extracted from a single center pci registry. the ...

conclusions although by current treatments, the prevalence of patients with low tc, ldl-c and non-hdl-c has significantly increased; dyslipidemia persisted in a considerable proportion of patients. these results necessitate further investigations into the relationship between high serum lipids and long-term outcome of patients after pci as well as further evaluations of the dyslipidemia treatme...

The outcome of percutaneous coronary interventions depends on several factors. Some relate to the patient's clinical characteristics, in particular, to the presence of diabetes, renal failure, or unstable syndromes, the number of diseased vessels, and the level of left ventricular function. Others are linked to the anatomical characteristics of the lesion. Firstly, whether it is located in the ...

136 The outcome of percutaneous coronary interventions depends on several factors. Some relate to the patient’s clinical characteristics, in particular, to the presence of diabetes, renal failure, or unstable syndromes, the number of diseased vessels, and the level of left ventricular function. Others are linked to the anatomical characteristics of the lesion. Firstly, whether it is located in ...

conclusions in total, application of therapeutic approaches in patients with cad depends on many factors. in our study not only risk factors such as gender, lifestyle, smoking, alcohol abuse, diabetes and hypertension were associated with the incidence of cad, but also they were highly correlated with the severity of the disease. results the mean age of total patients was 58.3 ± 11.5 years (p =...

BACKGROUND Increased experience and improvements in technology seem to have encouraged the use of percutaneous interventions for left main coronary artery (LMCA) occlusions. There is no consensus, however, and the data are inadequate on whether surgery or percutaneous procedures should be the intervention of choice for critical occlusions. METHODS From January 2002 to December 2006, 108 patie...