background and aims. irrational prescription of antibiotics by clinicians might lead to drug resistance. clinicians do prescribe antibiotics for either prophylactic or therapeutic reasons. the decision of when and what to prescribe leaves room for misuse and therefore it is imperative to continuously monitor knowledge and pattern of prescription. the aim of the present study was to determine th...

transurethral ureterolithotripsy (tul) is a frequently used procedure in urology departments. many urologists perform tul without antibiotic prophylaxis; however the use of chemoprophylaxis before tul remains a controversial issue in urology. thisstudy was carried out to assess the safety of omitting antibiotic prophylaxis prior to tul. in a prospective randomized clinical trial from january 20...

conclusions no correlation existed between cefazolin prophylaxis and postoperative infections in elective laparoscopic cholecystectomy patients. there may be an increased risk of infection in patients with previous cholecystitis or endoscopic retrograde cholangiopancreatography. in addition, there was an increased risk of postoperative infection in patients with gallbladder rupture and suction ...

BACKGROUND Although laparoscopic cholecystectomy (LC) is a common and widely applied technique, the use of antibiotics during the perioperative period in infection prevention remains controversial. In our study, a meta-analysis was performed to assess the impact of antibiotic prophylaxis on the postoperative infection rate in LC. METHODS A literature search was conducted on studies published ...

PURPOSE To elucidate Japanese trends for perioperative disinfection and antibiotic selection during cataract surgeries. METHODS Perioperative iodine use and antibiotic prophylaxis for cataract surgery were surveyed in eight regions in Japan by mail or through interviews from February 1 to March 1, 2014. RESULTS We surveyed 572 surgeons, of whom 386 (67%) responded. Most of the surgeons (94%...

BackgroundObesity is a risk factor for surgical site infections (SSI). Based on retrospective comparisons and pharmacology, many orthopedic centers have adopted weight- or body mass index (BMI)-related antibiotic prophylaxis.MethodsDouble-dose prophylaxis was introduced in March 2017 patients weighting >80 kg. The period April 2014 to (‘before’) compared the June 2019 (‘after’) regarding impact...

OBJECTIVES Deep sternal wound infection is a severe complication after cardiac surgery. Insufficient antibiotic target site concentrations may account for variable success of perioperative prophylaxis. Therefore, we measured perioperative penetration of cefazolin and of linezolid into sternal cancellous bone after sternotomy in coronary artery bypass grafting (CABG) patients by in vivo microdia...

BACKGROUND Unrestricted antibiotic use is very common in Iran. As a result, emergence of resistant organisms is commonplace. Antibiotic prophylaxis in surgery consists of a short antibiotic course given immediately before the procedure in order to prevent development of a surgical site infection. The basic principle of prophylaxis is to maintain effective concentrations of an antibiotic active ...

BACKGROUND AND PURPOSE Use of prophylactic antibiotics to prevent postoperative infection (POI) is a common practice in surgery. This study investigated the amount and cost of surgical prophylaxis in a representative general hospital in Taiwan in order to determine an appropriate course of action to control antibiotic use and decrease the burden of resistance. METHODS The use of antibiotic pr...