Since the introduction of the first angiotensin-converting enzyme inhibitor (ACEI), captopril, in 1981, ACEIs have become a mainstay of antihypertensive therapy. In addition to lowering blood pressure, there is overwhelming evidence that ACEIs (and angiotensin receptor blockers) provide end-organ protection independent of their blood pressure–lowering properties in diseases such as congestive h...

Perioperative myocardial infarction (PMI) is one of the most important causes for short and long term morbidity and mortality associated with non cardiac surgery. Prevention of a PMI is therefore of great importance in improving the overall outcome after non cardiac surgery. In the last few years, extensive research has been conducted into the causes of PMI. Yet, the exact causes of PMI remain ...

For associate degree nursing students at Eastern Kentucky University, Richmond, the perioperative nursing clinical experience typically included a one-day observation of a surgical procedure, with students entering the OR suite after the surgery started and having to leave before the surgery was completed. An associate professor of nursing and a perioperative staff education coordinator partner...

Most anesthesiologists will experience the perioperative death of a patient or a major perioperative catastrophe in the course of their careers. Anesthesia training, however, does not prepare individuals to handle the aftermath of such a stressful event. Multiple surveys have shown that the death of a patient has a major emotional impact on up to 75% of health care providers involved, regardles...

BACKGROUND Rheumatoid arthritis (RA) is associated with an increased risk of myocardial infarction (MI) and post-MI fatality compared with the general population. In a previous study examining post-MI treatment in RA compared with controls we noted that a higher proportion of the RA patients had experienced MI following a surgical procedure. The aim of this study was to compare the risk of MI a...

Abstract Funding Acknowledgements Type of funding sources: None. Background The rapid haemodynamics deterioration and presence myocardial ischemia early after cardiac surgical operations is a complex life threatening condition where diagnosis management fundamental importance. Objective: to analyse the factors associated with mortality patients post cardiotomy MI study role emergency coronary a...

During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 m...

During a 4-year multicenter cooperative study of acquired factor VIII inhibitors in persons with hemophilia A. new inhibitors were detected in 31 of 1 .306 patients who entered the study without an inhibitor or the history of an inhibitor. The incidence of new inhibitors was eight per 1 .000 patient-years of observation. The factor Vlll:C level before inhibitor development was 0.03 U/mi in 29 m...