Bone augmentation via tissue engineering has generated significant interest. We hypothesized that periosteum-derived cells could be used in place of bone marrow stromal cells (which are widely used) in bone engineering, but the differences in osteogenic potential between these 2 cell types are unclear. Here, we compared the osteogenic potential of these cells, and investigated the optimal osteo...

Lateral patellar dislocations can damage the medial patella femoral ligament. Nonoperative care is preferred but some tears may require a surgical intervention. Patella fractures are considered a risk factor after surgery. The technique described in this Technical Note avoids any bone tunnel drilling, which may eliminate the possibility of a patella fracture. The surgical procedure uses periost...

OBJECTIVE To characterize equine muscle tissue- and periosteal tissue-derived cells as mesenchymal stem cells (MSCs) and assess their proliferation capacity and osteogenic potential in comparison with bone marrow- and adipose tissue-derived MSCs. SAMPLE Tissues from 10 equine cadavers. PROCEDURES Cells were isolated from left semitendinosus muscle tissue, periosteal tissue from the distomed...

Congenital pseudarthrosis of the tibia is an uncommon manifestation of neurofibromatosis type 1 (NF1), but one that remains difficult to treat due to anabolic deficiency and catabolic excess. Bone grafting and more recently recombinant human bone morphogenetic proteins (rhBMPs) have been identified as pro-anabolic stimuli with the potential to improve the outcome after surgery. As an additional...

Discussion | Periosteal ganglia are uncommon single or multiloculatedsubcutaneouscysticnodules.These lesionsare rarely encounteredbydermatologists and areusually seen in the orthopedic setting.Althoughdescribedmainly inmen, these lesions also have been reported1,2 in children. Periosteal ganglia typically involvethetibia,but reports2-4havealsodescribed involvementof themedialmalleolus, femur, i...

Introduction: Coverage of bone grafts is very important in reconstructive surgery. In edentulous alveolar ridges this coverage is particularly important for supporting dental prostheses. Here we present the case of a patient with a large deficient maxillary anterior region that was reconstructed with a bilateral palatal submucosal periosteal connective tissue flap: a soft tissue reserve for up...

Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative response of the cells in the periosteum was similar. These studies have shown that neither bone f...

The patient, a 45-year-old male, was referred to the rheumatology clinic due to diffuse joint pain on the wrists and knees. The patient was diagnosed with liver cirrhosis and severe hepatopulmonary syndrome. Physical examination showed swelling of the knees and wrists (arthritis) and clubbing. The X-rays requested showed periosteal thickening observed continuously, in a diaphysometaphysiary loc...