Infectious endocarditis is multisystem disease, which the result of infection (usually bacterial) endocardial heart surface. Despite latest medical achievements in diagnostics and treatment, infectious still a disease with high mortality rate severe complications. During last decades developed countries there are obvious changes demographic characteristics patients endocarditis, namely increasi...

BACKGROUND Tropical idiopathic lower limb gangrene (TILLG) is also known as Symmetrical gangrene in the African, Idiopathic gangrene in the African and Idiopathic peripheral gangrene of the tropics. The aetiopathogenesis of this clinical entity is a mystery. OBJECTIVE To review methods of diagnosing tropical idiopathic lower limb gangrene (TILLG) and highlight its clinical variants. METHOD ...

Serious anaphylactic reactions to anesthetics can be life-threatening events. Vecuronium is promoted as a neuromuscular blocking drug that least likely cause anaphylaxis due its low histamine-releasing potential. Perioperative hypoxemia in patients with tetralogy of Fallot (TOF) easily misdiagnosed anoxic spells. We report patient TOF who suffered from symmetrical peripheral gangrene after unde...

RATIONALE We present 4 cases of symmetrical peripheral gangrene (SPG) associated with use of inotropic agent to elevate blood pressure. SPG is a relatively rare phenomenon characterized by symmetrical distal ischemic damage that leads to gangrene of 2 or more sites in the absence of large blood vessel obstruction, where vasoconstriction rather than thrombosis is implicated as the underlying pat...

We report a case of a 75-year-old Hispanic man treated for septic shock after undergoing surgery for impacted renal stones. He was given vasopressors and later developed symmetrical peripheral gangrene (SPG) on both his feet and left hand. SPG is a serious and rare condition presenting clinically as an acute onset of ischaemia with no vessel occlusion. Vasopressors are identified as a contribut...