OBJECTIVE To study the prevalence of Group A beta haemolytic Streptococcus in patients with acute pharyngitis and correlation of Modified Centor Score and Rapid Antigen Detection Test. METHODS The multi-centre, prospective, cross-sectional study was conducted in 8 major cities of Pakistan between June 2012 and February 2013, and comprised patients presenting with acute pharyngitis. The subjec...

It has recently been suggested that Chlamydia trachomatis may be a common cause of acute pharyngitis in adults. In a prospective investigation of 95 college students with acute pharyngitis, C. trachomatis was not isolated from any pharyngeal cultures. Further investigations are needed to better define the role of C. trachomatis in upper respiratory tract infections.

Bacterial oropharyngeal infections in healthy young people rarely give rise to life threatening complications. Lemierre's disease, caused by Fusobacetrium necrophorum, manifests as pharyngitis, jugular venous thrombosis and septic pulmonary embolism. A previously fit young male presenting with prolonged pharyngitis, complicated by severe pneumonia and septicaemia is presented. Recognition of th...

BACKGROUND How to use clinical score, the rapid streptococcal antigen test (RSAT), and culture results is uncertain for efficient management of acute pharyngitis in adults. METHODS This prospective cohort study included 372 adult patients with pharyngitis treated at a Swiss university-based primary care clinic. In eligible patients with 2 to 4 clinical symptoms and signs (temperature >or=38 d...

Fusobacterium necrophorum (Fn), a gram-negative anaerobe, is increasingly implicated as an etiologic agent in older adolescents and young adults with sore throat. Inadequately treated Fn pharyngitis may result in suppurative complications such as peritonsillar abscess and Lemierre's syndrome. Data from the literature suggest that the incidence of life-threating complications in these age groups...